Cargando…

Pharmacodynamic Studies of Fluorescent Diamond Carriers of Doxorubicin in Liver Cancer Cells and Colorectal Cancer Organoids

BACKGROUND: We recently reported on preferential deposition of bare fluorescent diamond particles FDP-NV-700/800nm (FDP-NV) in the liver following intravenous administration to rats. The pharmacokinetics of FDP-NV in that species indicated short residency in the circulation by rapid clearance by the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Firestein, Ron, Marcinkiewicz, Cezary, Nie, Linyan, Chua, Hui Kheng, Velazquez Quesada, Ines, Torelli, Marco, Sternberg, Mark, Gligorijevic, Bojana, Shenderova, Olga, Schirhagl, Romana, Feuerstein, Giora Z
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8434926/ https://www.ncbi.nlm.nih.gov/pubmed/34522092 http://dx.doi.org/10.2147/NSA.S321725

Ejemplares similares

Effects of Fluorescent Diamond Particles FDP-NV-800nm on Essential Biochemical Functions of Primary Human Umbilical Vein Cells and Human Hepatic Cell Line, HepG-2 in vitro (Part VI): Acute Biocompatibility Studies
por: Marcinkiewicz, Cezary, et al.
Publicado: (2020)

Biocompatibility studies of fluorescent diamond particles-(NV)~800nm (part V): in vitro kinetics and in vivo localization in rat liver following long-term exposure
por: Gerstenhaber, Jonathan A, et al.
Publicado: (2019)

Long-term biocompatibility of fluorescent diamonds-(NV)-Z~800 nm in rats: survival, morbidity, histopathology, particle distribution and excretion studies (part IV)
por: Barone, Frank C, et al.
Publicado: (2019)

Bitistatin-functionalized fluorescent nanodiamond particles specifically bind to purified human platelet integrin receptor α(IIb)β(3) and activated platelets
por: Marcinkiewicz, Cezary, et al.
Publicado: (2017)

Diamond Relaxometry as a Tool to Investigate the Free Radical Dialogue between Macrophages and Bacteria
por: Wu, Kaiqi, et al.
Publicado: (2023)

Relaxometry with Nitrogen Vacancy (NV) Centers in Diamond
por: Mzyk, Aldona, et al.
Publicado: (2022)

The Use of Near-Infrared Light-Emitting Fluorescent Nanodiamond Particles to Detect Ebola Virus Glycoprotein: Technology Development and Proof of Principle
por: Feuerstein, Giora Z, et al.
Publicado: (2020)

Review Article: Synthesis, properties, and applications of fluorescent diamond particles
por: Shenderova, Olga A., et al.
Publicado: (2019)

Vascular thrombus imaging in vivo via near-infrared fluorescent nanodiamond particles bioengineered with the disintegrin bitistatin (Part II)
por: Gerstenhaber, Jonathan A, et al.
Publicado: (2017)

Pilot study on biocompatibility of fluorescent nanodiamond-(NV)-Z~800 particles in rats: safety, pharmacokinetics, and bio-distribution (part III)
por: Barone, Frank C, et al.
Publicado: (2018)

NATO Advanced Research Workshop on Synthesis, Properties and Applications of Ultrananocrystalline Diamond
por: Gruen, Dieter M, et al.
Publicado: (2005)

Lipid peroxidation in diamond supported bilayers
por: Ortiz Moreno, A. R., et al.
Publicado: (2023)

The Response of HeLa Cells to Fluorescent NanoDiamond Uptake
por: Hemelaar, Simon R., et al.
Publicado: (2018)

Fast, Broad-Band Magnetic Resonance Spectroscopy with Diamond Widefield Relaxometry
por: Mignon, Charles, et al.
Publicado: (2023)

Micro Versus Macro – The Effect of Environmental Confinement on Cellular Nanoparticle Uptake
por: Damle, Viraj G., et al.
Publicado: (2020)

pH Sensitive Dextran Coated Fluorescent Nanodiamonds as a Biomarker for HeLa Cells Endocytic Pathway and Increased Cellular Uptake
por: Nie, Linyan, et al.
Publicado: (2021)

Diamond Quantum Sensing Revealing the Relation between Free Radicals and Huntington’s Disease
por: Fan, S., et al.
Publicado: (2023)

Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy
por: He, Peng, et al.
Publicado: (2022)

Invadopodia in context
por: Bergman, Aviv, et al.
Publicado: (2014)

Multiparametric Classification Links Tumor Microenvironments with Tumor Cell Phenotype
por: Gligorijevic, Bojana, et al.
Publicado: (2014)

Intracellular Quantum Sensing of Free-Radical Generation Induced by Acetaminophen (APAP) in the Cytosol, in Mitochondria and the Nucleus of Macrophages
por: Sharmin, Rokshana, et al.
Publicado: (2022)

Nanotechnology from lab to industry – a look at current trends
por: Rambaran, Theresa, et al.
Publicado: (2022)

Clot Imaging Using Photostable Nanodiamond
por: Francis, Samuel J., et al.
Publicado: (2023)

Unravelling Mechanisms of Doxorubicin-Induced Toxicity in 3D Human Intestinal Organoids
por: Rodrigues, Daniela, et al.
Publicado: (2022)

Background-free dual-mode optical and (13)C magnetic resonance imaging in diamond particles
por: Lv, Xudong, et al.
Publicado: (2021)

Smart probe for simultaneous detection of copper ion, pyrophosphate, and alkaline phosphatase in vitro and in clinical samples
por: Kiran, Sonia, et al.
Publicado: (2019)

Intracellular Relaxometry, Challenges, and Future Directions
por: Sigaeva, Alina, et al.
Publicado: (2022)

Invadopodia enable cooperative invasion and metastasis of breast cancer cells
por: Perrin, Louisiane, et al.
Publicado: (2022)

From Snake Venom’s Disintegrins and C-Type Lectins to Anti-Platelet Drugs
por: Lazarovici, Philip, et al.
Publicado: (2019)

Improving surface and defect center chemistry of fluorescent nanodiamonds for imaging purposes—a review
por: Nagl, Andreas, et al.
Publicado: (2015)

Adherent but Not Suspension-Cultured Embryoid Bodies Develop into Laminated Retinal Organoids
por: Radojevic, Bojana, et al.
Publicado: (2021)

HPHT-treated diamonds: diamonds forever
por: Dobrinets, Inga A, et al.
Publicado: (2013)

Effect of Dimeric Disintegrins Isolated from Vipera lebetina obtusa Venom on Glioblastoma Cellular Responses
por: Galicka, Anna, et al.
Publicado: (2023)

Visualization of Actin Polymerization in Invasive Structures of Macrophages and Carcinoma Cells Using Photoconvertible β-Actin – Dendra2 Fusion Proteins
por: Dovas, Athanassios, et al.
Publicado: (2011)

Dendra2 Photoswitching through the Mammary Imaging Window
por: Gligorijevic, Bojana, et al.
Publicado: (2009)

5'-Nucleotidase activity and arachidonate metabolism in doxorubicin sensitive and resistant P388 cells.
por: Ramu, A., et al.
Publicado: (1984)

In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization
por: Mody, Hardik, et al.
Publicado: (2023)

Contact guidance is cell cycle-dependent
por: Esmaeili Pourfarhangi, Kamyar, et al.
Publicado: (2018)

Nanodiamond for Sample Preparation in Proteomics
por: Perona Martinez, Felipe, et al.
Publicado: (2019)

5th European Conference on Diamond, Diamond-like and Related Materials : Diamond Films '94
Publicado: (1994)

Cannot write session to /tmp/vufind_sessions/sess_ft0gh2otf9056vg23mbi5uos2p