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Tlr2 Gene Deletion Delays Retinal Degeneration in Two Genetically Distinct Mouse Models of Retinitis Pigmentosa
Although considered a rare retinal dystrophy, retinitis pigmentosa (RP) is the primary cause of hereditary blindness. Given its diverse genetic etiology (>3000 mutations in >60 genes), there is an urgent need for novel treatments that target common features of the disease. TLR2 is a key activa...
Autores principales: | Sánchez-Cruz, Alonso, Méndez, Andrea C., Lizasoain, Ignacio, de la Villa, Pedro, de la Rosa, Enrique J., Hernández-Sánchez, Catalina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435220/ https://www.ncbi.nlm.nih.gov/pubmed/34360582 http://dx.doi.org/10.3390/ijms22157815 |
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