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Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology

In this contribution, a first-order time scheme is proposed for finding solutions to partial differential equations (PDEs). A mathematical model of the COVID-19 epidemic is modified where the recovery rate of exposed individuals is also considered. The linear stability of the equilibrium states for...

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Autores principales: Nawaz, Yasir, Arif, Muhammad Shoaib, Ashraf, Muhammad Usman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435406/
https://www.ncbi.nlm.nih.gov/pubmed/34539151
http://dx.doi.org/10.1007/s40995-021-01214-0
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author Nawaz, Yasir
Arif, Muhammad Shoaib
Ashraf, Muhammad Usman
author_facet Nawaz, Yasir
Arif, Muhammad Shoaib
Ashraf, Muhammad Usman
author_sort Nawaz, Yasir
collection PubMed
description In this contribution, a first-order time scheme is proposed for finding solutions to partial differential equations (PDEs). A mathematical model of the COVID-19 epidemic is modified where the recovery rate of exposed individuals is also considered. The linear stability of the equilibrium states for the modified COVID-19 model is given by finding its Jacobian and applying Routh–Hurwitz criteria on characteristic polynomial. The proposed scheme provides the first-order accuracy in time and second-order accuracy in space. The stability of the proposed scheme is given using the von Neumann stability criterion for standard parabolic PDEs. The consistency for the proposed scheme is also given by expanding the involved terms in it using the Taylor series. The scheme can be used to obtain the condition of getting a positive solution. The stability region of the scheme can be enlarged by choosing suitable values of the contained parameter. Finally, a comparison of the proposed scheme is made with the existing non-standard finite difference method. The results indicate that the non-standard classical technique is incapable of preserving the unique characteristics of the model’s epidemiologically significant solutions, whereas the proposed approaches are capable of doing so. A computational code for the proposed discrete model scheme may be made available to readers upon request for convenience.
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spelling pubmed-84354062021-09-13 Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology Nawaz, Yasir Arif, Muhammad Shoaib Ashraf, Muhammad Usman Iran J Sci Technol Trans A Sci Research Paper In this contribution, a first-order time scheme is proposed for finding solutions to partial differential equations (PDEs). A mathematical model of the COVID-19 epidemic is modified where the recovery rate of exposed individuals is also considered. The linear stability of the equilibrium states for the modified COVID-19 model is given by finding its Jacobian and applying Routh–Hurwitz criteria on characteristic polynomial. The proposed scheme provides the first-order accuracy in time and second-order accuracy in space. The stability of the proposed scheme is given using the von Neumann stability criterion for standard parabolic PDEs. The consistency for the proposed scheme is also given by expanding the involved terms in it using the Taylor series. The scheme can be used to obtain the condition of getting a positive solution. The stability region of the scheme can be enlarged by choosing suitable values of the contained parameter. Finally, a comparison of the proposed scheme is made with the existing non-standard finite difference method. The results indicate that the non-standard classical technique is incapable of preserving the unique characteristics of the model’s epidemiologically significant solutions, whereas the proposed approaches are capable of doing so. A computational code for the proposed discrete model scheme may be made available to readers upon request for convenience. Springer International Publishing 2021-09-13 2021 /pmc/articles/PMC8435406/ /pubmed/34539151 http://dx.doi.org/10.1007/s40995-021-01214-0 Text en © Shiraz University 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Research Paper
Nawaz, Yasir
Arif, Muhammad Shoaib
Ashraf, Muhammad Usman
Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title_full Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title_fullStr Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title_full_unstemmed Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title_short Development of Explicit Schemes for Diffusive SEAIR COVID-19 Epidemic Spreading Model: An Application to Computational Biology
title_sort development of explicit schemes for diffusive seair covid-19 epidemic spreading model: an application to computational biology
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435406/
https://www.ncbi.nlm.nih.gov/pubmed/34539151
http://dx.doi.org/10.1007/s40995-021-01214-0
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