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Curcumin improves memory deficits by inhibiting HMGB1‐RAGE/TLR4‐NF‐κB signalling pathway in APPswe/PS1dE9 transgenic mice hippocampus

Amyloid‐β (Aβ) deposition in the brain has been implicated in the development of Alzheimer's disease (AD), and neuroinflammation generates AD progression. Therapeutic effects of anti‐inflammatory approaches in AD are still under investigation. Curcumin, a potent anti‐inflammatory and antioxidan...

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Detalles Bibliográficos
Autores principales: Han, Yuan, Chen, Rui, Lin, Qicheng, Liu, Yu, Ge, Wenwei, Cao, Hong, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435415/
https://www.ncbi.nlm.nih.gov/pubmed/34405526
http://dx.doi.org/10.1111/jcmm.16855