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Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda

Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral swine disease that causes reproductive failure in breeding sows and respiratory distress in growing pigs. The main objectives were to simulate the transmission patterns of PRRS in Uganda using North American Animal Disease Spread Model...

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Autores principales: Hasahya, Emmanuel, Thakur, Krishna K., Dione, Michel M., Wieland, Barbara, Oba, Peter, Kungu, Joseph, Lee, Hu Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435599/
https://www.ncbi.nlm.nih.gov/pubmed/34527717
http://dx.doi.org/10.3389/fvets.2021.727895
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author Hasahya, Emmanuel
Thakur, Krishna K.
Dione, Michel M.
Wieland, Barbara
Oba, Peter
Kungu, Joseph
Lee, Hu Suk
author_facet Hasahya, Emmanuel
Thakur, Krishna K.
Dione, Michel M.
Wieland, Barbara
Oba, Peter
Kungu, Joseph
Lee, Hu Suk
author_sort Hasahya, Emmanuel
collection PubMed
description Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral swine disease that causes reproductive failure in breeding sows and respiratory distress in growing pigs. The main objectives were to simulate the transmission patterns of PRRS in Uganda using North American Animal Disease Spread Model (NAADSM) and to evaluate the potential effect of prevention and control options such as vaccination and movement control. The median number of infectious farms at the end of 52 weeks for the baseline scenario was 735 (36.75% of the 2,000 farms). The best effects of vaccination were observed in scenarios 60% farm coverage and 80% farm coverage, which resulted in 82 and 98.2% reduction in the median number of infectious farms at the end of the simulation, respectively. Vaccination of all medium and large farms only (33% of the farms) resulted in a 71.2% decrease in the median number of infectious farms at the end of 52 weeks. Movement control (MC) results showed that the median number of infectious farms at the end of 52 weeks decreased by 21.6, 52.3, 79.4, and 92.4% for scenarios MC 20, MC 40, MC 60, and MC 80%, respectively. This study provides new insights to the government of Uganda on how PRRS can be controlled. The large and medium farms need to be prioritized for vaccination, which would be a feasible and effective way to limit the spread of PRRS in Uganda. Scavenging pigs should be confined at all times, whether in the presence or absence of any disease outbreaks.
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spelling pubmed-84355992021-09-14 Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda Hasahya, Emmanuel Thakur, Krishna K. Dione, Michel M. Wieland, Barbara Oba, Peter Kungu, Joseph Lee, Hu Suk Front Vet Sci Veterinary Science Porcine Reproductive and Respiratory Syndrome (PRRS) is a viral swine disease that causes reproductive failure in breeding sows and respiratory distress in growing pigs. The main objectives were to simulate the transmission patterns of PRRS in Uganda using North American Animal Disease Spread Model (NAADSM) and to evaluate the potential effect of prevention and control options such as vaccination and movement control. The median number of infectious farms at the end of 52 weeks for the baseline scenario was 735 (36.75% of the 2,000 farms). The best effects of vaccination were observed in scenarios 60% farm coverage and 80% farm coverage, which resulted in 82 and 98.2% reduction in the median number of infectious farms at the end of the simulation, respectively. Vaccination of all medium and large farms only (33% of the farms) resulted in a 71.2% decrease in the median number of infectious farms at the end of 52 weeks. Movement control (MC) results showed that the median number of infectious farms at the end of 52 weeks decreased by 21.6, 52.3, 79.4, and 92.4% for scenarios MC 20, MC 40, MC 60, and MC 80%, respectively. This study provides new insights to the government of Uganda on how PRRS can be controlled. The large and medium farms need to be prioritized for vaccination, which would be a feasible and effective way to limit the spread of PRRS in Uganda. Scavenging pigs should be confined at all times, whether in the presence or absence of any disease outbreaks. Frontiers Media S.A. 2021-08-30 /pmc/articles/PMC8435599/ /pubmed/34527717 http://dx.doi.org/10.3389/fvets.2021.727895 Text en Copyright © 2021 Hasahya, Thakur, Dione, Wieland, Oba, Kungu and Lee. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Hasahya, Emmanuel
Thakur, Krishna K.
Dione, Michel M.
Wieland, Barbara
Oba, Peter
Kungu, Joseph
Lee, Hu Suk
Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title_full Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title_fullStr Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title_full_unstemmed Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title_short Modeling the Spread of Porcine Reproductive and Respiratory Syndrome Among Pig Farms in Lira District of Northern Uganda
title_sort modeling the spread of porcine reproductive and respiratory syndrome among pig farms in lira district of northern uganda
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435599/
https://www.ncbi.nlm.nih.gov/pubmed/34527717
http://dx.doi.org/10.3389/fvets.2021.727895
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