Cargando…

Radiation Induces Valvular Interstitial Cell Calcific Response in an in vitro Model of Calcific Aortic Valve Disease

Background: Mediastinal ionizing radiotherapy is associated with an increased risk of valvular disease, which demonstrates pathological hallmarks similar to calcific aortic valve disease (CAVD). Despite advances in radiotherapy techniques, the prevalence of comorbidities such as radiation-associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meerman, Manon, Driessen, Rob, van Engeland, Nicole C. A., Bergsma, Irith, Steenhuijsen, Jacco L. G., Kozono, David, Aikawa, Elena, Hjortnaes, Jesper, Bouten, Carlijn V. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435633/ https://www.ncbi.nlm.nih.gov/pubmed/34527708 http://dx.doi.org/10.3389/fcvm.2021.687885

Ejemplares similares

Standardization of Human Calcific Aortic Valve Disease in vitro Modeling Reveals Passage-Dependent Calcification
por: Goto, Shinji, et al.
Publicado: (2019)

Dissecting Calcific Aortic Valve Disease—The Role, Etiology, and Drivers of Valvular Fibrosis
por: Büttner, Petra, et al.
Publicado: (2021)

Semicarbazide-Sensitive Amine Oxidase Increases in Calcific Aortic Valve Stenosis and Contributes to Valvular Interstitial Cell Calcification
por: Mercier, Nathalie, et al.
Publicado: (2020)

Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells
por: Xiao, Fan, et al.
Publicado: (2021)

Quantification of Calcified Particles in Human Valve Tissue Reveals Asymmetry of Calcific Aortic Valve Disease Development
por: Yabusaki, Katsumi, et al.
Publicado: (2016)

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells
por: Carracedo, Miguel, et al.
Publicado: (2019)

Myocardial Disease and Long-Distance Space Travel: Solving the Radiation Problem
por: Meerman, Manon, et al.
Publicado: (2021)

Comparing the Role of Mechanical Forces in Vascular and Valvular Calcification Progression
por: Gomel, Madeleine A., et al.
Publicado: (2019)

Editorial: Heart Valve Tissue Engineering: Are We Ready for Clinical Translation?
por: Hjortnaes, Jesper, et al.
Publicado: (2021)

Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation
por: Hjortnaes, Jesper, et al.
Publicado: (2010)

Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification
por: Artiach, Gonzalo, et al.
Publicado: (2020)

Integrative Multi-Omics Analysis in Calcific Aortic Valve Disease Reveals a Link to the Formation of Amyloid-Like Deposits
por: Heuschkel, Marina A., et al.
Publicado: (2020)

Robust Generation of Quiescent Porcine Valvular Interstitial Cell Cultures
por: Porras, Ana M., et al.
Publicado: (2017)

miR-214 Attenuates Aortic Valve Calcification by Regulating Osteogenic Differentiation of Valvular Interstitial Cells
por: Li, Ning, et al.
Publicado: (2020)

Celastrol Alleviates Aortic Valve Calcification Via Inhibition of NADPH Oxidase 2 in Valvular Interstitial Cells
por: Liu, Huibing, et al.
Publicado: (2019)

Extracellular Vesicles As Mediators of Cardiovascular Calcification
por: Bakhshian Nik, Amirala, et al.
Publicado: (2017)

Editorial: Extracellular vesicles in cardiovascular inflammation and calcification
por: Krohn, Jona B., et al.
Publicado: (2022)

Organ Culture Model of Aortic Valve Calcification
por: Chester, Adrian H., et al.
Publicado: (2021)

Sevelamer Attenuates Bioprosthetic Heart Valve Calcification
por: Meng, Zhen, et al.
Publicado: (2021)

Multi-omics of in vitro aortic valve calcification
por: Semenova, Daria, et al.
Publicado: (2022)

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro
por: Lobov, Arseniy A., et al.
Publicado: (2022)

Reply: Evaluating Calcification in Tissue-Engineered Heart Valves: Much More Complicated Than Expected?
por: van der Valk, Dewy C., et al.
Publicado: (2023)

Regular Dietary Intake of Palmitate Causes Vascular and Valvular Calcification in a Rabbit Model
por: Donis, Nathalie, et al.
Publicado: (2021)

Dantrolene inhibits lysophosphatidylcholine-induced valve interstitial cell calcific nodule formation via blockade of the ryanodine receptor
por: Sylvester, Christopher B., et al.
Publicado: (2023)

Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis
por: Laguna-Fernandez, Andres, et al.
Publicado: (2016)

Treatment with XAV-939 prevents in vitro calcification of human valvular interstitial cells
por: Dittfeld, Claudia, et al.
Publicado: (2018)

Comparison of Serotonin-Regulated Calcific Processes in Aortic and Mitral Valvular Interstitial Cells
por: Wang, Xinmei, et al.
Publicado: (2021)

NOTCH Signaling in Aortic Valve Development and Calcific Aortic Valve Disease
por: Wang, Yidong, et al.
Publicado: (2021)

Autotaxin and Lipoprotein Metabolism in Calcific Aortic Valve Disease
por: Mathieu, Patrick, et al.
Publicado: (2019)

The Genetic Regulation of Aortic Valve Development and Calcific Disease
por: Menon, Vinal, et al.
Publicado: (2018)

MicroRNA-34c Inhibits Osteogenic Differentiation and Valvular Interstitial Cell Calcification via STC1-Mediated JNK Pathway in Calcific Aortic Valve Disease
por: Yang, Lieming, et al.
Publicado: (2020)

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
por: Iqbal, Farwah, et al.
Publicado: (2023)

Cathepsin S As an Inhibitor of Cardiovascular Inflammation and Calcification in Chronic Kidney Disease
por: Sena, Brena F., et al.
Publicado: (2018)

Potential ferroptosis key genes in calcific aortic valve disease
por: Li, Xiong-Zhi, et al.
Publicado: (2022)

Cellular Mechanisms of Valvular Thickening in Early and Intermediate Calcific Aortic Valve Disease
por: Ohukainen, Pauli, et al.
Publicado: (2018)

Valve Interstitial Cells: The Key to Understanding the Pathophysiology of Heart Valve Calcification
por: Rutkovskiy, Arkady, et al.
Publicado: (2017)

Calcification in Pulmonary Heart Valve Tissue Engineering: A Systematic Review and Meta-Analysis of Large-Animal Studies
por: van der Valk, Dewy C., et al.
Publicado: (2023)

Computational Screening Strategy for Drug Repurposing Identified Niclosamide as Inhibitor of Vascular Calcification
por: Tanaka, Takeshi, et al.
Publicado: (2022)

Serum Calcification Propensity and Calcification of the Abdominal Aorta in Patients With Primary Aldosteronism
por: Kantauskaite, Marta, et al.
Publicado: (2022)

Hypoxia-inducible factor activation promotes osteogenic transition of valve interstitial cells and accelerates aortic valve calcification in a mice model of chronic kidney disease
por: Csiki, Dávid Máté, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_srhcbm97kdrnbm4i0nh6tobspg