Bidirectional epithelial–mesenchymal crosstalk provides self-sustaining profibrotic signals in pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is the prototypic progressive fibrotic lung disease with a median survival of 2 to 4 years. Injury to and/or dysfunction of the alveolar epithelium is strongly implicated in IPF disease initiation, but the factors that determine whether fibrosis progresses rather...

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Detalles Bibliográficos
Autores principales: Yao, Liudi, Zhou, Yilu, Li, Juanjuan, Wickens, Leanne, Conforti, Franco, Rattu, Anna, Ibrahim, Fathima Maneesha, Alzetani, Aiman, Marshall, Ben G., Fletcher, Sophie V., Hancock, David, Wallis, Tim, Downward, Julian, Ewing, Rob M., Richeldi, Luca, Skipp, Paul, Davies, Donna E., Jones, Mark G., Wang, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435701/
https://www.ncbi.nlm.nih.gov/pubmed/34418430
http://dx.doi.org/10.1016/j.jbc.2021.101096

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