Cargando…

A Review of CYP3A Drug-Drug Interaction Studies: Practical Guidelines for Patients Using Targeted Oral Anticancer Drugs

Many oral anticancer drugs are metabolized by CYP3A. Clinical drug-drug interaction (DDI) studies often only examine the effect of strong CYP3A inhibitors and inducers. The effect of moderate or weak inhibitors or inducers can be examined using physiologically based pharmacokinetic simulations, but...

Descripción completa

Detalles Bibliográficos
Autores principales:	Molenaar-Kuijsten, Laura, Van Balen, Dorieke E. M., Beijnen, Jos H., Steeghs, Neeltje, Huitema, Alwin D. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435708/ https://www.ncbi.nlm.nih.gov/pubmed/34526892 http://dx.doi.org/10.3389/fphar.2021.670862

Ejemplares similares

Practical Recommendations for Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology
por: Verheijen, Remy B., et al.
Publicado: (2017)

Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs
por: Damoiseaux, David, et al.
Publicado: (2022)

Beta-adrenergic receptor blockade in angiosarcoma: Which beta-blocker to choose?
por: Embaby, Alaa, et al.
Publicado: (2022)

The influence of body mass index on the tolerability and effectiveness of full-weight-based paclitaxel chemotherapy in women with early-stage breast cancer
por: Lin, Lishi, et al.
Publicado: (2022)

Therapeutic drug monitoring of oral targeted antineoplastic drugs
por: Mueller-Schoell, Anna, et al.
Publicado: (2020)

Worse capecitabine treatment outcome in patients with a low skeletal muscle mass is not explained by altered pharmacokinetics
por: Molenaar‐Kuijsten, Laura, et al.
Publicado: (2021)

Representativeness of Phase III Trial for Osimertinib in Pretreated Advanced EGFR-Mutated Non-small-cell Lung Cancer Patients and Treatment Outcomes in Clinical Practice
por: Lin, Lishi, et al.
Publicado: (2021)

Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer
por: Crombag, Marie-Rose B.S., et al.
Publicado: (2016)

Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol
por: Mc Laughlin, Anna M., et al.
Publicado: (2021)

Clinical practice guidelines for translating pharmacogenomic knowledge to bedside. Focus on anticancer drugs
por: Agúndez, José A. G., et al.
Publicado: (2014)

Clinical Pharmacokinetics and Pharmacodynamics of Pazopanib: Towards Optimized Dosing
por: Verheijen, Remy B., et al.
Publicado: (2017)

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites
por: F. Martins, Margarida L., et al.
Publicado: (2022)

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose
por: Roosendaal, Jeroen, et al.
Publicado: (2020)

Editorial: Therapeutic Drug Monitoring (TDM): A Useful Tool for Pediatric Pharmacology Applied to Routine Clinical Practice
por: Simeoli, Raffaele, et al.
Publicado: (2022)

Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology
por: van der Kleij, Maud B. A., et al.
Publicado: (2023)

Potential Metabolic Drug–Drug Interaction of Citrus aurantium L. (Rutaceae) Evaluating by Its Effect on 3 CYP450
por: Zhou, Lu, et al.
Publicado: (2018)

CYP3A5 Genotype-Dependent Drug-Drug Interaction Between Tacrolimus and Nifedipine in Chinese Renal Transplant Patients
por: Yang, Yilei, et al.
Publicado: (2021)

Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review
por: Verrest, Luka, et al.
Publicado: (2021)

Correction to: Influence of Malnutrition on the Pharmacokinetics of Drugs Used in the Treatment of Poverty-Related Diseases: A Systematic Review
por: Verrest, Luka, et al.
Publicado: (2021)

Pharmacokinetic Optimization of Everolimus Dosing in Oncology: A Randomized Crossover Trial
por: Verheijen, Remy B., et al.
Publicado: (2017)

Functional evaluation of cyclosporine metabolism by CYP3A4 variants and potential drug interactions
por: Kong, Qihui, et al.
Publicado: (2023)

Searching Synergistic Dose Combinations for Anticancer Drugs
por: Yin, Zuojing, et al.
Publicado: (2018)

Risk of Drug-Drug Interactions in Out-Hospital Drug Dispensings in France: Results From the DRUG-Drug Interaction Prevalence Study
por: Létinier, Louis, et al.
Publicado: (2019)

Editorial: Drug-drug interactions in pharmacology
por: Pichini, Simona, et al.
Publicado: (2023)

Opioid Drug-Drug-Drug Interactions and Unintentional Traumatic Injury: Screening to Detect Three-Way Drug Interaction Signals
por: Acton, Emily K., et al.
Publicado: (2022)

MicroRNA as an Important Target for Anticancer Drug Development
por: Fu, Zhiwen, et al.
Publicado: (2021)

The Mechanisms of Current Platinum Anticancer Drug Resistance in the Glioma
por: Lu, Enzhou, et al.
Publicado: (2022)

Prevalence of potential drug–drug interactions in cancer patients treated with oral anticancer drugs
por: van Leeuwen, R W F, et al.
Publicado: (2013)

The Chinese herb Styrax triggers pharmacokinetic herb-drug interactions via inhibiting intestinal CYP3A
por: Zhang, Feng, et al.
Publicado: (2022)

Managing Drug Interactions With Oral Anticancer Treatments
por: Lohr, Lisa K., et al.
Publicado: (2023)

Recommendations for Off-Label Drug Use in Ophthalmology in China: A Clinical Practice Guideline
por: Li, Guangyao, et al.
Publicado: (2022)

Harnessing soft tissue sarcoma with low-dose pazopanib – a matter of blood levels
por: Groenland, Stefanie L., et al.
Publicado: (2018)

Drug-Drug Interactions at Organic Cation Transporter 1
por: Zhou, Shiwei, et al.
Publicado: (2021)

Rediscovery of Traditional Plant Medicine: An Underestimated Anticancer Drug of Chelerythrine
por: Chen, Nianzhi, et al.
Publicado: (2022)

Small molecules targeting Pin1 as potent anticancer drugs
por: Zhang, Jing, et al.
Publicado: (2023)

Delamanid Coadministered with Antiretroviral Drugs or Antituberculosis Drugs Shows No Clinically Relevant Drug-Drug Interactions in Healthy Subjects
por: Mallikaarjun, Suresh, et al.
Publicado: (2016)

Analysis of Clinical Drug-Drug Interaction Data To Predict Magnitudes of Uncharacterized Interactions between Antiretroviral Drugs and Comedications
por: Stader, Felix, et al.
Publicado: (2018)

Screening for severe drug-drug interactions in patients with multiple sclerosis: A comparison of three drug interaction databases
por: Hecker, Michael, et al.
Publicado: (2022)

Advances in Oral Drug Delivery
por: Alqahtani, Mohammed S., et al.
Publicado: (2021)

Surface engineered mesoporous silica carriers for the controlled delivery of anticancer drug 5-fluorouracil: Computational approach for the drug-carrier interactions using density functional theory
por: Rehman, Fozia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_igbdn2kev4lvl8g24gko5n149b