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Microglia and Perivascular Macrophages Act as Antigen Presenting Cells to Promote CD8 T Cell Infiltration of the Brain
CD8 T cell infiltration of the central nervous system (CNS) is necessary for host protection but contributes to neuropathology. Antigen presenting cells (APCs) situated at CNS borders are thought to mediate T cell entry into the parenchyma during neuroinflammation. The identity of the CNS-resident A...
Autores principales: | Goddery, Emma N., Fain, Cori E., Lipovsky, Chloe G., Ayasoufi, Katayoun, Yokanovich, Lila T., Malo, Courtney S., Khadka, Roman H., Tritz, Zachariah P., Jin, Fang, Hansen, Michael J., Johnson, Aaron J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435747/ https://www.ncbi.nlm.nih.gov/pubmed/34526998 http://dx.doi.org/10.3389/fimmu.2021.726421 |
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