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Fatal cytokine release syndrome by an aberrant FLIP/STAT3 axis

Inflammatory responses rapidly detect pathogen invasion and mount a regulated reaction. However, dysregulated anti-pathogen immune responses can provoke life-threatening inflammatory pathologies collectively known as cytokine release syndrome (CRS), exemplified by key clinical phenotypes unearthed d...

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Detalles Bibliográficos
Autores principales: Musiu, Chiara, Caligola, Simone, Fiore, Alessandra, Lamolinara, Alessia, Frusteri, Cristina, Del Pizzo, Francesco Domenico, De Sanctis, Francesco, Canè, Stefania, Adamo, Annalisa, Hofer, Francesca, Barouni, Roza Maria, Grilli, Andrea, Zilio, Serena, Serafini, Paolo, Tacconelli, Evelina, Donadello, Katia, Gottin, Leonardo, Polati, Enrico, Girelli, Domenico, Polidoro, Ildo, Iezzi, Piera Amelia, Angelucci, Domenico, Capece, Andrea, Chen, Ying, Shi, Zheng-Li, Murray, Peter J., Chilosi, Marco, Amit, Ido, Bicciato, Silvio, Iezzi, Manuela, Bronte, Vincenzo, Ugel, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435761/
https://www.ncbi.nlm.nih.gov/pubmed/34518653
http://dx.doi.org/10.1038/s41418-021-00866-0