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High Counts of CD68+ and CD163+ Macrophages in Mantle Cell Lymphoma Are Associated With Inferior Prognosis

BACKGROUND: Lymphoma-associated macrophages (LAMs) are key components in the lymphoma microenvironment, which may impact disease progression and response to therapy. There are two major subtypes of LAMs, CD68+ M1 and CD163+ M2. M2 LAMs can be transformed from M1 LAMs, particularly in certain diffuse...

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Detalles Bibliográficos
Autores principales: Li, Philippa, Yuan, Ji, Ahmed, Fahad Shabbir, McHenry, Austin, Fu, Kai, Yu, Guohua, Cheng, Hongxia, Xu, Mina L., Rimm, David L., Pan, Zenggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435777/
https://www.ncbi.nlm.nih.gov/pubmed/34527580
http://dx.doi.org/10.3389/fonc.2021.701492