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Transduction Efficiency and Immunogenicity of Viral Vectors for Cochlear Gene Therapy: A Systematic Review of Preclinical Animal Studies
Background: Hearing impairment is the most frequent sensory deficit, affecting 466 million people worldwide and has been listed by the World Health Organization (WHO) as one of the priority diseases for research into therapeutic interventions to address public health needs. Inner ear gene therapy is...
Autores principales: | Verdoodt, Dorien, Peeleman, Noa, Van Camp, Guy, Van Rompaey, Vincent, Ponsaerts, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435788/ https://www.ncbi.nlm.nih.gov/pubmed/34526880 http://dx.doi.org/10.3389/fncel.2021.728610 |
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