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Alveolar macrophage transcriptomic profiling in COPD shows major lipid metabolism changes

BACKGROUND: Immune cells play a major role in the pathogenesis of COPD. Changes in the distribution and cellular functions of major immune cells, such as alveolar macrophages (AMs) and neutrophils are well known; however, their transcriptional reprogramming and contribution to the pathophysiology of...

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Detalles Bibliográficos
Autores principales: Fujii, Wataru, Kapellos, Theodore S., Baßler, Kevin, Händler, Kristian, Holsten, Lisa, Knoll, Rainer, Warnat-Herresthal, Stefanie, Oestreich, Marie, Hinkley, Emily R., Hasenauer, Jan, Pizarro, Carmen, Thiele, Christoph, Aschenbrenner, Anna C., Ulas, Thomas, Skowasch, Dirk, Schultze, Joachim L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435801/
https://www.ncbi.nlm.nih.gov/pubmed/34527724
http://dx.doi.org/10.1183/23120541.00915-2020