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Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn
Riluzole (2-amino-6-(trifluoromethoxy)benzothiazole) is a drug known for its inhibitory effect on glutamatergic transmission and its anti-nociceptive and anti-allodynic effects in neuropathic pain rat models. Riluzole also has an enhancing effect on GABAergic synaptic transmission. However, the effe...
Autores principales: | Taiji, Ryo, Yamanaka, Manabu, Taniguchi, Wataru, Nishio, Naoko, Tsutsui, Shunji, Nakatsuka, Terumasa, Yamada, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435917/ https://www.ncbi.nlm.nih.gov/pubmed/34541342 http://dx.doi.org/10.1016/j.bbrep.2021.101130 |
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