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Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn

Riluzole (2-amino-6-(trifluoromethoxy)benzothiazole) is a drug known for its inhibitory effect on glutamatergic transmission and its anti-nociceptive and anti-allodynic effects in neuropathic pain rat models. Riluzole also has an enhancing effect on GABAergic synaptic transmission. However, the effe...

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Detalles Bibliográficos
Autores principales: Taiji, Ryo, Yamanaka, Manabu, Taniguchi, Wataru, Nishio, Naoko, Tsutsui, Shunji, Nakatsuka, Terumasa, Yamada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8435917/
https://www.ncbi.nlm.nih.gov/pubmed/34541342
http://dx.doi.org/10.1016/j.bbrep.2021.101130

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