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Cobalt chloride-stimulated hypoxia promotes the proliferation of cholesteatoma keratinocytes via the PI3K/Akt signaling pathway

Herein, we purposed to explore whether hypoxia triggers proliferation of cholesteatoma keratinocytes via the PI3K-Akt signaling cascade. Cells were inoculated with different concentration of CoCl(2). The proliferation and cellular HIF-1α, p-PDK1 and p‑Akt expression levels of cholesteatoma keratinoc...

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Detalles Bibliográficos
Autores principales: Zhang, Chen, Chen, Min, Tao, Qi, Chi, Zhangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436096/
https://www.ncbi.nlm.nih.gov/pubmed/34522167
http://dx.doi.org/10.7150/ijms.60617

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