STING nuclear partners contribute to innate immune signaling responses

STimulator of INterferon Genes (STING) is an adaptor for cytoplasmic DNA sensing by cGAMP/cGAS that helps trigger innate immune responses (IIRs). Although STING is mostly localized in the ER, we find a separate inner nuclear membrane pool of STING that increases mobility and redistributes to the out...

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Detalles Bibliográficos
Autores principales: Dixon, Charles R., Malik, Poonam, de las Heras, Jose I., Saiz-Ros, Natalia, de Lima Alves, Flavia, Tingey, Mark, Gaunt, Eleanor, Richardson, A. Christine, Kelly, David A., Goldberg, Martin W., Towers, Greg J., Yang, Weidong, Rappsilber, Juri, Digard, Paul, Schirmer, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436130/
https://www.ncbi.nlm.nih.gov/pubmed/34541469
http://dx.doi.org/10.1016/j.isci.2021.103055

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