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PCSK9 is not secreted from mature differentiated intestinal cells

Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes lysosomal degradation of the LDL receptor and is a key regulator of cholesterol metabolism. After the liver, the small intestine is the second organ that highly expresses PCSK9. However, the small intestine's ability to secrete PCSK...

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Detalles Bibliográficos
Autores principales:	Moreau, François, Thédrez, Aurélie, Garçon, Damien, Ayer, Audrey, Sotin, Thibaud, Dijk, Wieneke, Blanchard, Claire, Chadeuf, Gilliane, Arnaud, Lucie, Croyal, Mikael, Van Landeghem, Laurianne, Touvron, Melissa, Prieur, Xavier, Roubtsova, Anna, Seidah, Nabil, Prat, Annik, Cariou, Bertrand, Le May, Cedric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436166/ https://www.ncbi.nlm.nih.gov/pubmed/34280453 http://dx.doi.org/10.1016/j.jlr.2021.100096

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