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‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomeg...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436267/ https://www.ncbi.nlm.nih.gov/pubmed/34527259 http://dx.doi.org/10.1093/omcr/omab086 |
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author | Miącz, Karolina Śledź, Jakub Karwacki, Marek W |
author_facet | Miącz, Karolina Śledź, Jakub Karwacki, Marek W |
author_sort | Miącz, Karolina |
collection | PubMed |
description | Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomegaly. A nonspecific lesion in the axillary region with a homogenous nodal reaction was found, combined with a history of a tick-bite in the pectoral muscle. Primary differentiation included leukemia, lymphoma, mononucleosis, borrelial lymphoma and simple abscess. All of the above were excluded. A further search for diagnosis focused on tick-borne diseases: TIBOLa or anaplasmosis. The ulceroglandular tularemia was eventually confirmed serologically. Besides the fact that tularemia is a rare diagnosis nowadays, it is still necessary to include this disease in the differentiation of a nonresolving tick-bite abscess with lymphadenopathy. Diagnostic vigilance is the key to effective treatment because other obvious symptoms such as severe anemia might delay the diagnosis. |
format | Online Article Text |
id | pubmed-8436267 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-84362672021-09-14 ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ Miącz, Karolina Śledź, Jakub Karwacki, Marek W Oxf Med Case Reports Case Report Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomegaly. A nonspecific lesion in the axillary region with a homogenous nodal reaction was found, combined with a history of a tick-bite in the pectoral muscle. Primary differentiation included leukemia, lymphoma, mononucleosis, borrelial lymphoma and simple abscess. All of the above were excluded. A further search for diagnosis focused on tick-borne diseases: TIBOLa or anaplasmosis. The ulceroglandular tularemia was eventually confirmed serologically. Besides the fact that tularemia is a rare diagnosis nowadays, it is still necessary to include this disease in the differentiation of a nonresolving tick-bite abscess with lymphadenopathy. Diagnostic vigilance is the key to effective treatment because other obvious symptoms such as severe anemia might delay the diagnosis. Oxford University Press 2021-09-13 /pmc/articles/PMC8436267/ /pubmed/34527259 http://dx.doi.org/10.1093/omcr/omab086 Text en © The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Miącz, Karolina Śledź, Jakub Karwacki, Marek W ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title | ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title_full | ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title_fullStr | ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title_full_unstemmed | ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title_short | ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
title_sort | ‘unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436267/ https://www.ncbi.nlm.nih.gov/pubmed/34527259 http://dx.doi.org/10.1093/omcr/omab086 |
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