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‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’

Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomeg...

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Autores principales: Miącz, Karolina, Śledź, Jakub, Karwacki, Marek W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436267/
https://www.ncbi.nlm.nih.gov/pubmed/34527259
http://dx.doi.org/10.1093/omcr/omab086
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author Miącz, Karolina
Śledź, Jakub
Karwacki, Marek W
author_facet Miącz, Karolina
Śledź, Jakub
Karwacki, Marek W
author_sort Miącz, Karolina
collection PubMed
description Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomegaly. A nonspecific lesion in the axillary region with a homogenous nodal reaction was found, combined with a history of a tick-bite in the pectoral muscle. Primary differentiation included leukemia, lymphoma, mononucleosis, borrelial lymphoma and simple abscess. All of the above were excluded. A further search for diagnosis focused on tick-borne diseases: TIBOLa or anaplasmosis. The ulceroglandular tularemia was eventually confirmed serologically. Besides the fact that tularemia is a rare diagnosis nowadays, it is still necessary to include this disease in the differentiation of a nonresolving tick-bite abscess with lymphadenopathy. Diagnostic vigilance is the key to effective treatment because other obvious symptoms such as severe anemia might delay the diagnosis.
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spelling pubmed-84362672021-09-14 ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’ Miącz, Karolina Śledź, Jakub Karwacki, Marek W Oxf Med Case Reports Case Report Tularemia is a disease caused by Francisella tularensis—gram-negative coccobacillus. The ulceroglandular type characterized by skin ulcers and painful regional adenopathy is recognized as the most common. A 1-year-old patient was admitted with severe normocytic anemia, high fever and hepatosplenomegaly. A nonspecific lesion in the axillary region with a homogenous nodal reaction was found, combined with a history of a tick-bite in the pectoral muscle. Primary differentiation included leukemia, lymphoma, mononucleosis, borrelial lymphoma and simple abscess. All of the above were excluded. A further search for diagnosis focused on tick-borne diseases: TIBOLa or anaplasmosis. The ulceroglandular tularemia was eventually confirmed serologically. Besides the fact that tularemia is a rare diagnosis nowadays, it is still necessary to include this disease in the differentiation of a nonresolving tick-bite abscess with lymphadenopathy. Diagnostic vigilance is the key to effective treatment because other obvious symptoms such as severe anemia might delay the diagnosis. Oxford University Press 2021-09-13 /pmc/articles/PMC8436267/ /pubmed/34527259 http://dx.doi.org/10.1093/omcr/omab086 Text en © The Author(s) 2021. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
Miącz, Karolina
Śledź, Jakub
Karwacki, Marek W
‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title_full ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title_fullStr ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title_full_unstemmed ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title_short ‘Unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
title_sort ‘unique does not mean impossible: infant presenting with complicated course of ulceroglandular tularemia.’
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436267/
https://www.ncbi.nlm.nih.gov/pubmed/34527259
http://dx.doi.org/10.1093/omcr/omab086
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