ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) emerged in December 2019(1,2) and is responsible for the COVID-19 pandemic3. Vaccines are an essential countermeasure urgently needed to control the pandemic4. Here, we show that the adenovirus-vectored vaccine ChAdOx1 nCoV-19, encoding th...

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Detalles Bibliográficos
Autores principales: van Doremalen, Neeltje, Lambe, Teresa, Spencer, Alexandra, Belij-Rammerstorfer, Sandra, Purushotham, Jyothi N., Port, Julia R., Avanzato, Victoria A., Bushmaker, Trenton, Flaxman, Amy, Ulaszewska, Marta, Feldmann, Friederike, Allen, Elizabeth R., Sharpe, Hannah, Schulz, Jonathan, Holbrook, Myndi, Okumura, Atsushi, Meade-White, Kimberly, Pérez-Pérez, Lizzette, Edwards, Nick J., Wright, Daniel, Bissett, Cameron, Gilbride, Ciaran, Williamson, Brandi N., Rosenke, Rebecca, Long, Dan, Ishwarbhai, Alka, Kailath, Reshma, Rose, Louisa, Morris, Susan, Powers, Claire, Lovaglio, Jamie, Hanley, Patrick W., Scott, Dana, Saturday, Greg, de Wit, Emmie, Gilbert, Sarah C., Munster, Vincent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436420/
https://www.ncbi.nlm.nih.gov/pubmed/32731258
http://dx.doi.org/10.1038/s41586-020-2608-y

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