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Follistatin supplementation induces changes in CDX2 CpG methylation and improves in vitro development of bovine SCNT preimplantation embryos

Caudal Type Homeobox 2 (CDX2) is a key regulator of trophectoderm formation and maintenance in preimplantation embryos. We previously demonstrated that supplementation of exogenous follistatin, during in vitro culture of bovine IVF embryos, upregulates CDX2 expression, possibly, via alteration of th...

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Detalles Bibliográficos
Autores principales: Ashry, Mohamed, Yang, Chunyan, Rajput, Sandeep K., Folger, Joseph K., Knott, Jason G., Smith, George W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436481/
https://www.ncbi.nlm.nih.gov/pubmed/34517901
http://dx.doi.org/10.1186/s12958-021-00829-7