Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with neuronal cell inclusions composed of neurofilaments and other abnormal aggregative proteins as pathological hallmarks. Approximately 90% of patients have sporadic cases (sALS), and at least 4 genes, i.e....

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Detalles Bibliográficos
Autores principales: Lin, Feng, Lin, Wanhui, Zhu, Chaofeng, Lin, Jilan, Zhu, Junge, Li, Xu-Ying, Wang, Zhanjun, Wang, Chaodong, Huang, Huapin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436554/
https://www.ncbi.nlm.nih.gov/pubmed/34511133
http://dx.doi.org/10.1186/s12920-021-01073-z

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