Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury

BACKGROUND: Spinal cord injury (SCI) is a severe traumatic disease which causes high disability and mortality rates. The molecular pathological features after spinal cord injury mainly involve the inflammatory response, microglial and neuronal apoptosis, abnormal proliferation of astrocytes, and the...

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Detalles Bibliográficos
Autores principales: Rong, Yuluo, Ji, Chengyue, Wang, Zhuanghui, Ge, Xuhui, Wang, Jiaxing, Ye, Wu, Tang, Pengyu, Jiang, Dongdong, Fan, Jin, Yin, Guoyong, Liu, Wei, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436564/
https://www.ncbi.nlm.nih.gov/pubmed/34511129
http://dx.doi.org/10.1186/s12974-021-02268-y

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