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Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine

BACKGROUND: Human Papillomavirus type 16 (HPV16) has been associated with a subset of head and neck cancers. Two HPV encoded oncogenic proteins, E6 and E7, are important for the malignant progression of HPV-associated cancers. A spontaneous HPV16 E6/E7-expressing oral tumor model in human HLA-A2 (AA...

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Detalles Bibliográficos
Autores principales: Tseng, Ssu-Hsueh, Liu, Li, Peng, Shiwen, Kim, Jinhwi, Ferrall, Louise, Hung, Chien-Fu, Wu, T. -C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436567/
https://www.ncbi.nlm.nih.gov/pubmed/34517865
http://dx.doi.org/10.1186/s12929-021-00759-x