IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome

Analysis of serum cytokine levels in Wiskott–Aldrich syndrome patients pre‐ and post‐ treatment reveals IL‐18 as a stable and reliable marker of inflammation. Definitive stem cell treatment with good myeloid correction correlates with resolution of inflammation and reduction of circulating IL‐18, hi...

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Autores principales: Rivers, Elizabeth, Hong, Ying, Bajaj‐Elliott, Mona, Worth, Austen, Thrasher, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Letters to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436742/
https://www.ncbi.nlm.nih.gov/pubmed/33448368
http://dx.doi.org/10.1002/eji.202049024
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author Rivers, Elizabeth
Hong, Ying
Bajaj‐Elliott, Mona
Worth, Austen
Thrasher, Adrian J.
author_facet Rivers, Elizabeth
Hong, Ying
Bajaj‐Elliott, Mona
Worth, Austen
Thrasher, Adrian J.
author_sort Rivers, Elizabeth
collection PubMed
description Analysis of serum cytokine levels in Wiskott–Aldrich syndrome patients pre‐ and post‐ treatment reveals IL‐18 as a stable and reliable marker of inflammation. Definitive stem cell treatment with good myeloid correction correlates with resolution of inflammation and reduction of circulating IL‐18, highlighting the importance of actin cytoskeletal regulation of myeloid cells in control of inflammation. [Image: see text]
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spelling pubmed-84367422021-09-17 IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome Rivers, Elizabeth Hong, Ying Bajaj‐Elliott, Mona Worth, Austen Thrasher, Adrian J. Eur J Immunol Letters to the Editor Analysis of serum cytokine levels in Wiskott–Aldrich syndrome patients pre‐ and post‐ treatment reveals IL‐18 as a stable and reliable marker of inflammation. Definitive stem cell treatment with good myeloid correction correlates with resolution of inflammation and reduction of circulating IL‐18, highlighting the importance of actin cytoskeletal regulation of myeloid cells in control of inflammation. [Image: see text] John Wiley and Sons Inc. 2021-02-05 2021-05 /pmc/articles/PMC8436742/ /pubmed/33448368 http://dx.doi.org/10.1002/eji.202049024 Text en © 2021 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letters to the Editor
Rivers, Elizabeth
Hong, Ying
Bajaj‐Elliott, Mona
Worth, Austen
Thrasher, Adrian J.
IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title_full IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title_fullStr IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title_full_unstemmed IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title_short IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome
title_sort il‐18: a potential inflammation biomarker in wiskott–aldrich syndrome
topic Letters to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436742/
https://www.ncbi.nlm.nih.gov/pubmed/33448368
http://dx.doi.org/10.1002/eji.202049024
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