Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease

BACKGROUND: GBA mutations are a common risk factor for Parkinson's disease (PD). A recent study has suggested that GBA haplotypes, identified by intronic variants, can affect age at diagnosis of PD. OBJECTIVES: In this study, we assess this hypothesis using long reads across a large cohort and...

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Detalles Bibliográficos
Autores principales: Toffoli, Marco, Higgins, Abigail, Lee, Chiao, Koletsi, Sofia, Chen, Xiao, Eberle, Michael, Sedlazeck, Fritz J., Mullin, Stephen, Proukakis, Christos, Schapira, Anthony H.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Regular Issue Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436748/
https://www.ncbi.nlm.nih.gov/pubmed/34008887
http://dx.doi.org/10.1002/mds.28616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436748/
https://www.ncbi.nlm.nih.gov/pubmed/34008887
http://dx.doi.org/10.1002/mds.28616

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