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Intronic Haplotypes in the GBA Gene Do Not Predict Age at Diagnosis of Parkinson's Disease

BACKGROUND: GBA mutations are a common risk factor for Parkinson's disease (PD). A recent study has suggested that GBA haplotypes, identified by intronic variants, can affect age at diagnosis of PD. OBJECTIVES: In this study, we assess this hypothesis using long reads across a large cohort and...

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Detalles Bibliográficos
Autores principales:	Toffoli, Marco, Higgins, Abigail, Lee, Chiao, Koletsi, Sofia, Chen, Xiao, Eberle, Michael, Sedlazeck, Fritz J., Mullin, Stephen, Proukakis, Christos, Schapira, Anthony H.V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Regular Issue Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436748/ https://www.ncbi.nlm.nih.gov/pubmed/34008887 http://dx.doi.org/10.1002/mds.28616

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