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25-Hydroxycholesterol protecting from cerebral ischemia-reperfusion injury through the inhibition of STING activity

Middle cerebral artery occlusion (MCAO) injury refers to impaired blood supply to the brain that is caused by a cerebrovascular disease, resulting in local brain tissue ischemia, hypoxic necrosis, and rapid neurological impairment. Nevertheless, the mechanisms involved are unclear, and pharmacologic...

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Detalles Bibliográficos
Autores principales: Lin, Feihong, Yao, Xinyu, Kong, Chang, Liu, Xia, Zhao, Zhangfan, Rao, Suhuan, Wang, Lu, Li, Shan, Wang, Junlu, Dai, Qinxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436919/
https://www.ncbi.nlm.nih.gov/pubmed/34406977
http://dx.doi.org/10.18632/aging.203337