Proteomic characterization of secretory granules in dopaminergic neurons indicates chromogranin/secretogranin-mediated protein processing impairment in Parkinson’s disease

Parkinson’s disease (PD) is an aging disorder related to vesicle transport dysfunctions and neurotransmitter secretion. Secretory granules (SGs) are large dense-core vesicles for the biosynthesis of neuropeptides and hormones. At present, the involvement of SGs impairment in PD remains unclear. In t...

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Detalles Bibliográficos
Autores principales: Wen, Gehua, Pang, Hao, Wu, Xu, Jiang, Enzhu, Zhang, Xique, Zhan, Xiaoni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436928/
https://www.ncbi.nlm.nih.gov/pubmed/34420933
http://dx.doi.org/10.18632/aging.203415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436928/
https://www.ncbi.nlm.nih.gov/pubmed/34420933
http://dx.doi.org/10.18632/aging.203415

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