Cargando…

Proteomic characterization of secretory granules in dopaminergic neurons indicates chromogranin/secretogranin-mediated protein processing impairment in Parkinson’s disease

Parkinson’s disease (PD) is an aging disorder related to vesicle transport dysfunctions and neurotransmitter secretion. Secretory granules (SGs) are large dense-core vesicles for the biosynthesis of neuropeptides and hormones. At present, the involvement of SGs impairment in PD remains unclear. In t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Gehua, Pang, Hao, Wu, Xu, Jiang, Enzhu, Zhang, Xique, Zhan, Xiaoni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8436928/ https://www.ncbi.nlm.nih.gov/pubmed/34420933 http://dx.doi.org/10.18632/aging.203415

Ejemplares similares

An antibody against secretogranin I (chromogranin B) is packaged into secretory granules
Publicado: (1989)

Regulatory Peptides from Chromogranin A and Secretogranin II
por: Helle, Karen B.
Publicado: (2010)

Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364–384))
por: Biswas, Nilima, et al.
Publicado: (2010)

Fecal chromogranins and secretogranins are linked to the fecal and mucosal intestinal bacterial composition of IBS patients and healthy subjects
por: Sundin, Johanna, et al.
Publicado: (2018)

Secretory granule protein chromogranin B (CHGB) forms an anion channel in membranes
por: Yadav, Gaya P, et al.
Publicado: (2018)

Isolation and Proteomics of the Insulin Secretory Granule
por: Norris, Nicholas, et al.
Publicado: (2021)

Proteomic profiling of secretory granules of different T cell subpopulations
por: Schmidt, H, et al.
Publicado: (2009)

Secretogranins I and II: two tyrosine-sulfated secretory proteins common to a variety of cells secreting peptides by the regulated pathway
Publicado: (1985)

Binding of microtubules to pituitary secretory granules and secretory granule membranes
Publicado: (1977)

Essential Role of the Disulfide-bonded Loop of Chromogranin B for Sorting to Secretory Granules Is Revealed by Expression of a Deletion Mutant in the Absence of Endogenous Granin Synthesis
por: Krömer, Andreas, et al.
Publicado: (1998)

Parkinson's disease and dopaminergic neurons
Publicado: (2012)

Lipid-dependent deposition of alpha-synuclein and Tau on neuronal Secretogranin II-positive vesicular membranes with age
por: Brekk, Oeystein R., et al.
Publicado: (2018)

Dynamics of peptidergic secretory granule transport are regulated by neuronal stimulation
por: Sobota, Jacqueline A, et al.
Publicado: (2010)

Parkinson’s Disease, the Dopaminergic Neuron and Gammahydroxybutyrate
por: Mamelak, Mortimer
Publicado: (2018)

Chromogranin A, the major lumenal protein in chromaffin granules, controls fusion pore expansion
por: Abbineni, Prabhodh S., et al.
Publicado: (2019)

Conditional knockout of the secretogranin II gene to reveal biological functions of secretoneurin
por: Leierer, Johannes, et al.
Publicado: (2008)

Secretogranin II influences the assembly and function of MHC class I in melanoma
por: Steinfass, Tamara, et al.
Publicado: (2023)

Inside the Insulin Secretory Granule
por: Germanos, Mark, et al.
Publicado: (2021)

Transport via the regulated secretory pathway in semi-intact PC12 cells: role of intra-cisternal calcium and pH in the transport and sorting of secretogranin II
Publicado: (1994)

Characterization of the immature secretory granule, an intermediate in granule biogenesis
Publicado: (1991)

TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3
por: Schecterson, Leslayann C., et al.
Publicado: (2020)

Vulnerability of Mesostriatal Dopaminergic Neurons in Parkinson's Disease
por: González-Hernández, Tomás, et al.
Publicado: (2010)

Mysterious inhibitory cell regulator investigated and found likely to be secretogranin II related
por: Hart, John E., et al.
Publicado: (2017)

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy
por: LeBlanc, Michelle E., et al.
Publicado: (2017)

Epitope mapping of an uncertain endogenous antigen implies secretogranin II peptide splicing
por: Howlett, David R., et al.
Publicado: (2019)

Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells
por: Schmidt, Hendrik, et al.
Publicado: (2011)

Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling
por: Li, Min, et al.
Publicado: (2018)

Neuron-specific enolase and chromogranin A as markers of neuroendocrine tumours.
por: Baudin, E., et al.
Publicado: (1998)

Zymophagy: Selective Autophagy of Secretory Granules
por: Vaccaro, Maria I.
Publicado: (2012)

Secretory granule formation: The morphologist’s view
por: Tooze, John
Publicado: (1991)

Biogenesis of Dense-Core Secretory Granules
por: Bowman, Grant R., et al.
Publicado: (2010)

ISOLATION AND PROPERTIES OF SECRETORY GRANULES FROM RAT ISLETS OF LANGERHANS : I. Isolation of a Secretory Granule Fraction
por: Howell, S. L., et al.
Publicado: (1969)

Roles of FGF20 in dopaminergic neurons and Parkinson's disease
por: Itoh, Nobuyuki, et al.
Publicado: (2013)

Secretogranin II; a Protein Increased in the Myocardium and Circulation in Heart Failure with Cardioprotective Properties
por: Røsjø, Helge, et al.
Publicado: (2012)

Secretogranin III Selectively Promotes Vascular Leakage in the Deep Vascular Plexus of Diabetic Retinopathy
por: Ji, Liyang, et al.
Publicado: (2023)

Regulation of secretory granule size by the precise generation and fusion of unit granules
por: Hammel, Ilan, et al.
Publicado: (2010)

Polyamines Are Present in Mast Cell Secretory Granules and Are Important for Granule Homeostasis
por: García-Faroldi, Gianni, et al.
Publicado: (2010)

Cerebrospinal Fluid Levels of Chromogranin A in Parkinson’s Disease and Multiple System Atrophy
por: Kaiserova, Michaela, et al.
Publicado: (2021)

Secretogranin II impairs tumor growth and angiogenesis by promoting degradation of hypoxia‐inducible factor‐1α in colorectal cancer
por: Fang, Chao, et al.
Publicado: (2021)

Accumulation of adrenocorticotropin secretory granules in the midbody of telophase AtT20 cells: evidence that secretory granules move anterogradely along microtubules
Publicado: (1987)

Cannot write session to /tmp/vufind_sessions/sess_tr83cc8suppteejnv8ki2fj8pe