Multitrait GWAS to connect disease variants and biological mechanisms

Genome-wide association studies (GWASs) have uncovered a wealth of associations between common variants and human phenotypes. Here, we present an integrative analysis of GWAS summary statistics from 36 phenotypes to decipher multitrait genetic architecture and its link with biological mechanisms. Ou...

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Detalles Bibliográficos
Autores principales: Julienne, Hanna, Laville, Vincent, McCaw, Zachary R., He, Zihuai, Guillemot, Vincent, Lasry, Carla, Ziyatdinov, Andrey, Nerin, Cyril, Vaysse, Amaury, Lechat, Pierre, Ménager, Hervé, Le Goff, Wilfried, Dube, Marie-Pierre, Kraft, Peter, Ionita-Laza, Iuliana, Vilhjálmsson, Bjarni J., Aschard, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437297/
https://www.ncbi.nlm.nih.gov/pubmed/34460823
http://dx.doi.org/10.1371/journal.pgen.1009713

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