Cargando…

Gephyrin and CYP2C9 Genetic Polymorphisms in Patients with Pharmacoresistant Epilepsy

PURPOSE: Gephyrin (GPHN) is an essential protein in the regulation of inhibitory postsynaptic density and polymorphism in the corresponding gene may have a role in the development of pharmacoresistant epilepsy (PRE). For the first time, we aimed to evaluate the association of rs928553T/C variants wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Tallawy, Hamdy N, Abuhamdah, Sawsan, Nassar, Ahmed Y, Farghaly, Wafaa M A, Saleem, Tahia H, Atta, Sara A, Sayed, Ayat A, Tohamy, Amal M, Hassan, Mohammed H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437390/ https://www.ncbi.nlm.nih.gov/pubmed/34526803 http://dx.doi.org/10.2147/PGPM.S327808

Ejemplares similares

Spectrum of epilepsy – prevalence, impact, and treatment gap: an epidemiological study from Al-Quseir, Egypt
por: El-Tallawy, Hamdy N, et al.
Publicado: (2016)

Cortical stimulation in pharmacoresistant focal epilepsies
por: Ellrich, Jens
Publicado: (2020)

Genetic variations associated with pharmacoresistant epilepsy
por: Cárdenas-Rodríguez, Noemí, et al.
Publicado: (2020)

Construction and Standardization of Dementia Arabic Scale
por: Farghaly, Wafaa M, et al.
Publicado: (2021)

Clinical and biochemical study of d-serine metabolism among schizophrenia patients
por: El-Tallawy, Hamdy N, et al.
Publicado: (2017)

Vagal nerve stimulation for pharmacoresistant epilepsy in children
por: Hauptman, Jason S., et al.
Publicado: (2012)

Improving Therapy of Pharmacoresistant Epilepsies: The Role of Fenfluramine
por: Dini, Gianluca, et al.
Publicado: (2022)

Pharmacoresistant Abdominal Seizures in Symptomatic Localization-Related Epilepsy
por: Tushar, Vadakke Puthanveetil, et al.
Publicado: (2021)

The Pharmacoresistant Epilepsy: An Overview on Existant and New Emerging Therapies
por: Fattorusso, Antonella, et al.
Publicado: (2021)

Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level?
por: Czornyj, Liliana, et al.
Publicado: (2021)

Corrigendum: Improving therapy of pharmacoresistant epilepsies: The role of fenfluramine
por: Dini, Gianluca, et al.
Publicado: (2023)

Impact of nocturnal sleep deprivation on declarative memory retrieval in students at an orphanage: a psychoneuroradiological study
por: Tantawy, Ahmed O, et al.
Publicado: (2013)

Effect of Oxidative Stress on ABC Transporters: Contribution to Epilepsy Pharmacoresistance
por: Grewal, Gurpreet Kaur, et al.
Publicado: (2017)

A complex systems view on the current hypotheses of epilepsy pharmacoresistance
por: Servilha‐Menezes, Gabriel, et al.
Publicado: (2022)

Effects of Surgical Side and Site on Mood and Behavior Outcome in Children with Pharmacoresistant Epilepsy
por: Andresen, Elizabeth N., et al.
Publicado: (2014)

Impaired formation of high-order gephyrin oligomers underlies gephyrin dysfunction-associated pathologies
por: Kim, Seungjoon, et al.
Publicado: (2021)

Epileptic and cognitive changes in children with cerebral palsy: an Egyptian study
por: El-Tallawy, Hamdy N, et al.
Publicado: (2014)

Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy
por: Yoon, Jung-Rim, et al.
Publicado: (2013)

7T MRI with post-processing for the presurgical evaluation of pharmacoresistant focal epilepsy
por: Chen, Cong, et al.
Publicado: (2021)

‘Hippocampal innate inflammatory gliosis only’ in pharmacoresistant temporal lobe epilepsy
por: Grote, Alexander, et al.
Publicado: (2022)

Limbic network co‐localization predicts pharmacoresistance in dysplasia‐related epilepsy
por: Cohen, Nathan T., et al.
Publicado: (2023)

Bilateral stereotactic lesions and chronic stimulation of the anterior thalamic nuclei for treatment of pharmacoresistant epilepsy
por: Sitnikov, A. R., et al.
Publicado: (2018)

Knowledge of and Attitude towards Epilepsy among the Jordanian Community
por: Abuhamdah, Sawsan M. A., et al.
Publicado: (2022)

Cannabidiol in Pharmacoresistant Epilepsy: Clinical Pharmacokinetic Data From an Expanded Access Program
por: Contin, Manuela, et al.
Publicado: (2021)

Pharmacoresistant Epilepsy in Childhood: Think of the Cerebral Folate Deficiency, a Treatable Disease
por: Mafi, Sarah, et al.
Publicado: (2020)

Network Substrates of Centromedian Nucleus Deep Brain Stimulation in Generalized Pharmacoresistant Epilepsy
por: Torres Diaz, Cristina V., et al.
Publicado: (2021)

Multi‐omic strategies applied to the study of pharmacoresistance in mesial temporal lobe epilepsy
por: Bruxel, Estela M., et al.
Publicado: (2021)

Altered structural connectome in non-lesional newly diagnosed focal epilepsy: Relation to pharmacoresistance
por: Kreilkamp, Barbara A.K., et al.
Publicado: (2021)

Gephyrin, the enigmatic organizer at GABAergic synapses
por: Tretter, Verena, et al.
Publicado: (2012)

Construction of standardized Arabic questionnaires for screening neurological disorders (dementia, stroke, epilepsy, movement disorders, muscle and neuromuscular junction disorders)
por: El Tallawy, Hamdy N, et al.
Publicado: (2016)

Circulating Ubiquitin Carboxyl Terminal Hydrolase L1 and Neuroglobin Levels in Traumatic Spinal Cord Injuries: Relation to Severity and Outcomes
por: Abuhamdah, Sawsan, et al.
Publicado: (2022)

Construction of an Arabic computerized battery for cognitive rehabilitation of children with specific learning disabilities
por: Farghaly, Wafaa MA, et al.
Publicado: (2018)

Pharmacoresistant Epilepsy: A Current Update on Non-Conventional Pharmacological and Non-Pharmacological Interventions
por: Sharma, Arun Kumar, et al.
Publicado: (2015)

Chaotic and stochastic dynamics of epileptiform-like activities in sclerotic hippocampus resected from patients with pharmacoresistant epilepsy
por: Araújo, Noemi S., et al.
Publicado: (2022)

Radiological and Clinical Value of 7T MRI for Evaluating 3T-Visible Lesions in Pharmacoresistant Focal Epilepsies
por: Wang, Z. Irene, et al.
Publicado: (2021)

Gephyrin-Lacking PV Synapses on Neocortical Pyramidal Neurons
por: Kuljis, Dika A., et al.
Publicado: (2021)

Population-based study of acquired cerebellar ataxia in Al-Kharga district, New Valley, Egypt
por: Farghaly, Wafaa MA, et al.
Publicado: (2011)

A Clinical-EEG Study of Sleepiness and Psychological Symptoms in Pharmacoresistant Epilepsy Patients Treated with Lacosamide
por: Giorgi, Filippo S., et al.
Publicado: (2013)

Role of DNA Methylation and Adenosine in Ketogenic Diet for Pharmacoresistant Epilepsy: Focus on Epileptogenesis and Associated Comorbidities
por: Chen, Fan, et al.
Publicado: (2019)

Reduction in anti-seizure medications use in pediatric patients with pharmacoresistant epilepsy submitted to surgical treatment
por: de Matos, Maiave Micaelle Figueiredo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lkvs1lo3eteiao05aje41oe2vo