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Epidemiology of intussusception among infants in Togo, 2015-2018

INTRODUCTION: intussusception is the leading cause of bowel obstruction in infants and young children. We describe the epidemiology and diagnostic and treatment characteristics of intussusception among Togolese infants over a 4-year period. METHODS: we implemented active surveillance among infants y...

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Autores principales: Tsolenyanu, Enyonam, Akakpo-Numado, Komlatsè, Akolly, Djatougbe Eliane, Mwenda, Jason Mathiu, Tate, Jacqueline, Boko, Amevegbe, Landoh, Dadja, Gnassingne, Komlan, Atakouma, Yawo, Parashar, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437427/
https://www.ncbi.nlm.nih.gov/pubmed/34548899
http://dx.doi.org/10.11604/pamj.supp.2021.39.1.21343
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author Tsolenyanu, Enyonam
Akakpo-Numado, Komlatsè
Akolly, Djatougbe Eliane
Mwenda, Jason Mathiu
Tate, Jacqueline
Boko, Amevegbe
Landoh, Dadja
Gnassingne, Komlan
Atakouma, Yawo
Parashar, Umesh
author_facet Tsolenyanu, Enyonam
Akakpo-Numado, Komlatsè
Akolly, Djatougbe Eliane
Mwenda, Jason Mathiu
Tate, Jacqueline
Boko, Amevegbe
Landoh, Dadja
Gnassingne, Komlan
Atakouma, Yawo
Parashar, Umesh
author_sort Tsolenyanu, Enyonam
collection PubMed
description INTRODUCTION: intussusception is the leading cause of bowel obstruction in infants and young children. We describe the epidemiology and diagnostic and treatment characteristics of intussusception among Togolese infants over a 4-year period. METHODS: we implemented active surveillance among infants younger than 1 year of age admitted with intussusception from 2015 to 2018 at Sylvanus Olympio Teaching Hospital and in 2018 at Campus Teaching Hospital. Brighton Collaboration Level 1 case definition criteria were used to confirm the diagnosis of intussusception. RESULTS: during four years, 41 cases of intussusception, with an annual range of 8 to 14 cases (median: 10) were reported; and the highest number of cases (89%) was enrolled at Sylvanus Olympio teaching hospital. Intussusception was uncommon in the first 2 months of life, peaked from 5 to 7 months old (63%), with male predominance (63%), and showed no significant seasonality. One third of cases (34%) were transferred to the sentinel surveillance site from another health facility; and the median delay in seeking care was 4 days (range: 0-11) with ≥ 48-hour delay in 59% of cases. Clinical symptoms, ultrasound and surgery were combined to diagnose intussusception in all the cases (100%). The treatment was exclusively surgical, and intestinal resection was common (28/41, 68%). A high case fatality rate (23%) was observed and the average length of hospital stay was 10 days (range: 1-23). CONCLUSION: active surveillance for intussusception in Togo has highlighted exclusive use of surgical therapy; often associated to an intestinal resection with a very high case fatality rate.
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spelling pubmed-84374272021-09-20 Epidemiology of intussusception among infants in Togo, 2015-2018 Tsolenyanu, Enyonam Akakpo-Numado, Komlatsè Akolly, Djatougbe Eliane Mwenda, Jason Mathiu Tate, Jacqueline Boko, Amevegbe Landoh, Dadja Gnassingne, Komlan Atakouma, Yawo Parashar, Umesh Pan Afr Med J Research INTRODUCTION: intussusception is the leading cause of bowel obstruction in infants and young children. We describe the epidemiology and diagnostic and treatment characteristics of intussusception among Togolese infants over a 4-year period. METHODS: we implemented active surveillance among infants younger than 1 year of age admitted with intussusception from 2015 to 2018 at Sylvanus Olympio Teaching Hospital and in 2018 at Campus Teaching Hospital. Brighton Collaboration Level 1 case definition criteria were used to confirm the diagnosis of intussusception. RESULTS: during four years, 41 cases of intussusception, with an annual range of 8 to 14 cases (median: 10) were reported; and the highest number of cases (89%) was enrolled at Sylvanus Olympio teaching hospital. Intussusception was uncommon in the first 2 months of life, peaked from 5 to 7 months old (63%), with male predominance (63%), and showed no significant seasonality. One third of cases (34%) were transferred to the sentinel surveillance site from another health facility; and the median delay in seeking care was 4 days (range: 0-11) with ≥ 48-hour delay in 59% of cases. Clinical symptoms, ultrasound and surgery were combined to diagnose intussusception in all the cases (100%). The treatment was exclusively surgical, and intestinal resection was common (28/41, 68%). A high case fatality rate (23%) was observed and the average length of hospital stay was 10 days (range: 1-23). CONCLUSION: active surveillance for intussusception in Togo has highlighted exclusive use of surgical therapy; often associated to an intestinal resection with a very high case fatality rate. The African Field Epidemiology Network 2021-07-29 /pmc/articles/PMC8437427/ /pubmed/34548899 http://dx.doi.org/10.11604/pamj.supp.2021.39.1.21343 Text en ©Enyonam Tsolenyanu et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Tsolenyanu, Enyonam
Akakpo-Numado, Komlatsè
Akolly, Djatougbe Eliane
Mwenda, Jason Mathiu
Tate, Jacqueline
Boko, Amevegbe
Landoh, Dadja
Gnassingne, Komlan
Atakouma, Yawo
Parashar, Umesh
Epidemiology of intussusception among infants in Togo, 2015-2018
title Epidemiology of intussusception among infants in Togo, 2015-2018
title_full Epidemiology of intussusception among infants in Togo, 2015-2018
title_fullStr Epidemiology of intussusception among infants in Togo, 2015-2018
title_full_unstemmed Epidemiology of intussusception among infants in Togo, 2015-2018
title_short Epidemiology of intussusception among infants in Togo, 2015-2018
title_sort epidemiology of intussusception among infants in togo, 2015-2018
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437427/
https://www.ncbi.nlm.nih.gov/pubmed/34548899
http://dx.doi.org/10.11604/pamj.supp.2021.39.1.21343
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