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Hepatitis B virus genotypes prevalence in patients from hepatology services in Ceará, Brazil

INTRODUCTION: Hepatitis B virus (HBV) infection is a public health problem; therefore, we aimed to report HBV genotypes in Ceará, Brazil. METHODS: A total of 103 HBsAg-positive samples were subjected to HBV genotyping and subgenotyping. RESULTS: The following genetic compositions of samples were fou...

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Detalles Bibliográficos
Autores principales: Cruz, José Napoleão Monte Da, Villar, Lívia Melo, Mello, Francisco Campello Do Amaral, Lampe, Elisabeth, Hyppolito, Elodie Bomfim, Lima, José Milton De Castro, Hyppolito, Silvia Bomfim, Pires, Roberto Da Justa, Nicolete, Larissa Deadame De Figueiredo, Coelho, Ivo Castelo Branco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437444/
https://www.ncbi.nlm.nih.gov/pubmed/34495262
http://dx.doi.org/10.1590/0037-8682-0807-2020
Descripción
Sumario:INTRODUCTION: Hepatitis B virus (HBV) infection is a public health problem; therefore, we aimed to report HBV genotypes in Ceará, Brazil. METHODS: A total of 103 HBsAg-positive samples were subjected to HBV genotyping and subgenotyping. RESULTS: The following genetic compositions of samples were found: F-54% (F2-83.33%), A-40% (A1-65%), D-6%, C2-1%, E-1%, and G-1%. CONCLUSIONS: Some genotypes are only prevalent in certain parts of the world; however, the State of Ceará is a hub for migration and has one of the most important liver transplantation centers in Brazil, which can explain the prevalence of the F genotype.