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Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19
Some stem cell types not only release molecules that reduce viral replication, but also reduce the hypercytokinemia and inflammation induced by the immune system, and have been found to be part of the innate and adaptive immune systems. An important component of the stem cell’s ability to ameliorate...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437473/ https://www.ncbi.nlm.nih.gov/pubmed/34527167 http://dx.doi.org/10.1080/19420889.2021.1965356 |
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author | Maguire, Greg |
author_facet | Maguire, Greg |
author_sort | Maguire, Greg |
collection | PubMed |
description | Some stem cell types not only release molecules that reduce viral replication, but also reduce the hypercytokinemia and inflammation induced by the immune system, and have been found to be part of the innate and adaptive immune systems. An important component of the stem cell’s ability to ameliorate viral diseases, especially the complications post-clearance of the pathogen, is the ability of adult stem cells to reset the innate and adaptive immune systems from an inflammatory state to a repair state. Thus, the molecules released from certain stem cell types found to be safe and efficacious, may be an important new means for therapeutic development in Covid-19, especially for late-stage inflammation and tissue damage once the virus has cleared, particularly in the aged population. |
format | Online Article Text |
id | pubmed-8437473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-84374732021-09-14 Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 Maguire, Greg Commun Integr Biol Review Some stem cell types not only release molecules that reduce viral replication, but also reduce the hypercytokinemia and inflammation induced by the immune system, and have been found to be part of the innate and adaptive immune systems. An important component of the stem cell’s ability to ameliorate viral diseases, especially the complications post-clearance of the pathogen, is the ability of adult stem cells to reset the innate and adaptive immune systems from an inflammatory state to a repair state. Thus, the molecules released from certain stem cell types found to be safe and efficacious, may be an important new means for therapeutic development in Covid-19, especially for late-stage inflammation and tissue damage once the virus has cleared, particularly in the aged population. Taylor & Francis 2021-09-10 /pmc/articles/PMC8437473/ /pubmed/34527167 http://dx.doi.org/10.1080/19420889.2021.1965356 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Maguire, Greg Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title | Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title_full | Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title_fullStr | Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title_full_unstemmed | Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title_short | Stem cells part of the innate and adaptive immune systems as a therapeutic for Covid-19 |
title_sort | stem cells part of the innate and adaptive immune systems as a therapeutic for covid-19 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437473/ https://www.ncbi.nlm.nih.gov/pubmed/34527167 http://dx.doi.org/10.1080/19420889.2021.1965356 |
work_keys_str_mv | AT maguiregreg stemcellspartoftheinnateandadaptiveimmunesystemsasatherapeuticforcovid19 |