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Beneficial autoimmunity links primary biliary cholangitis to the avoidance of cholangiocarcinoma

It has been an open conundrum why primary sclerosing cholangitis (PSC) is a major risk factor for developing cholangiocarcinoma (CAA), while primary biliary cholangitis (PBC) is not. In mouse models of PSC and PBC, it turned out that the latter condition, an autoimmune disease affecting the bile duc...

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Detalles Bibliográficos
Autores principales: Pol, Jonathan G., Paillet, Juliette, Plantureux, Céleste, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437477/
https://www.ncbi.nlm.nih.gov/pubmed/34527429
http://dx.doi.org/10.1080/2162402X.2021.1968595