The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells

An oral antiviral against SARS-CoV-2 that also attenuates inflammatory instigators of severe COVID-19 is not available to date. Herein, we show that the apoA-I mimetic peptide 4 F inhibits Spike mediated viral entry and has antiviral activity against SARS-CoV-2 in human lung epithelial Calu3 and Ver...

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Detalles Bibliográficos
Autores principales: Theodoros, Kelesidis, Sharma, Madhav, Anton, Petcherski, Hugo, Cristelle, Ellen, O’Connor, Hultgren, Nan W, Ritou, Eleni, Williams, David S, Orian S, Shirihai, Srinivasa T, Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437485/
https://www.ncbi.nlm.nih.gov/pubmed/34494942
http://dx.doi.org/10.1080/21505594.2021.1964329

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