Cargando…

Aminoquinolines as Translational Models for Drug Repurposing: Anticancer Adjuvant Properties and Toxicokinetic-Related Features

The indiscriminate consumption of antimalarials against coronavirus disease-2019 emphasizes the longstanding clinical weapons of medicines. In this work, we conducted a review on the antitumor mechanisms of aminoquinolines, focusing on the responses and differences of tumor histological tissues and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferreira, Paulo Michel Pinheiro, Ferreira, José Roberto de Oliveira, de Sousa, Rayran Walter Ramos, Bezerra, Daniel Pereira, Militão, Gardenia Carmen Gadelha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437624/ https://www.ncbi.nlm.nih.gov/pubmed/34527050 http://dx.doi.org/10.1155/2021/3569349

Ejemplares similares

The Dual Antioxidant/Prooxidant Effect of Eugenol and Its Action in Cancer Development and Treatment
por: Bezerra, Daniel Pereira, et al.
Publicado: (2017)

Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization
por: McAnally, Danielle, et al.
Publicado: (2018)

Oxidative stress in the hippocampus during experimental seizures can be ameliorated with the antioxidant ascorbic acid
por: Santos, Ítala Mônica Sales, et al.
Publicado: (2009)

Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi
por: Lechuga, Guilherme Curty, et al.
Publicado: (2016)

Improving Riparin-A Dissolution through a Laponite Based Nanohybrid
por: Gomes, Duanne Mendes, et al.
Publicado: (2023)

Toxicokinetics of Kava
por: Rowe, Anthony, et al.
Publicado: (2011)

Antimalarials with Benzothiophene Moieties as Aminoquinoline Partners
por: Konstantinović, Jelena, et al.
Publicado: (2017)

The biological speciation and toxicokinetics of aluminum.
por: DeVoto, E, et al.
Publicado: (1994)

Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities
por: Solomon, V. Raja, et al.
Publicado: (2019)

Cobalt-Catalyzed Direct Carbonylation of Aminoquinoline Benzamides
por: Grigorjeva, Liene, et al.
Publicado: (2014)

Toxicokinetics of bone lead.
por: Rabinowitz, M B
Publicado: (1991)

Population toxicokinetics of benzene.
por: Bois, F Y, et al.
Publicado: (1996)

Toxicokinetics in Risk Evaluations
por: Punt, Ans
Publicado: (2018)

Methaemoglobinaemia and the radical curative efficacy of 8-aminoquinoline antimalarials
por: White, Nicholas J, et al.
Publicado: (2022)

Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives
por: Zhang, Haiwen, et al.
Publicado: (2008)

Putative Contribution of 8-Aminoquinolines to Preventing Recrudescence of Malaria
por: Markus, Miles B.
Publicado: (2023)

Toxicokinetics of Metformin During Hemodialysis
por: Ayoub, Paul, et al.
Publicado: (2017)

Synthesis and Antimycobacterial Evaluation of N-(4-(Benzyloxy)benzyl)-4-aminoquinolines
por: Grams, Estevão Silveira, et al.
Publicado: (2022)

Repurposing Tranexamic Acid as an Anticancer Agent
por: Law, Mary E., et al.
Publicado: (2022)

Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine
por: Lu, Lu, et al.
Publicado: (2020)

Increase of leishmanicidal and tubercular activities using steroids linked to aminoquinoline
por: Antinarelli, Luciana MR, et al.
Publicado: (2012)

Primaquine or other 8-aminoquinoline for reducing Plasmodium falciparum transmission
por: Graves, Patricia M, et al.
Publicado: (2015)

Primaquine or other 8-aminoquinoline for reducing P. falciparum transmission
por: Graves, Patricia M, et al.
Publicado: (2014)

Antimalarial and antimicrobial activities of 8-Aminoquinoline-Uracils metal complexes
por: Phopin, Kamonrat, et al.
Publicado: (2016)

Primaquine or other 8‐aminoquinolines for reducing Plasmodium falciparum transmission
por: Graves, Patricia M, et al.
Publicado: (2018)

Identification of 4-aminoquinoline core for the design of new cholinesterase inhibitors
por: Chen, Yao, et al.
Publicado: (2016)

4-Aminoquinoline compounds from the Spanish flu to COVID-19
por: Bazotte, Roberto Barbosa, et al.
Publicado: (2021)

Effect of PON1 on dichlorvos toxicokinetics
por: Wang, Na-Na, et al.
Publicado: (2010)

Effects of Ethanol on the Toxicokinetics of Methamphetamine in Rabbits
por: Li, Bing, et al.
Publicado: (2014)

Embryotoxicity and Toxicokinetics of the Antimalarial Artesunate in Rats
por: Chung, Moon-Koo, et al.
Publicado: (2013)

Mixture prioritization and testing: the importance of toxicokinetics
por: Braeuning, Albert, et al.
Publicado: (2021)

Toxicokinetics of Chromium in Enchytraeus crypticus (Oligochaeta)
por: Santos, Fátima C. F., et al.
Publicado: (2022)

The wisdom of crowds and the repurposing of artesunate as an anticancer drug
por: Augustin, Yolanda, et al.
Publicado: (2015)

Anticancer Properties of Fenofibrate: A Repurposing Use
por: Lian, Xin, et al.
Publicado: (2018)

Repurposing anticancer drugs for the management of COVID-19
por: El Bairi, Khalid, et al.
Publicado: (2020)

Fruit fly for anticancer drug discovery and repurposing
por: Nainu, Firzan, et al.
Publicado: (2023)

Mechanistic details of the cobalt-mediated dehydrogenative dimerization of aminoquinoline-directed benzamides
por: Xu, Li-Ping, et al.
Publicado: (2020)

Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine
por: Sahraei, Zahra, et al.
Publicado: (2020)

Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary
por: Silva, Bárbara, et al.
Publicado: (2022)

Fenitrothion: toxicokinetics and toxicologic evaluation in human volunteers.
por: Meaklim, Jean, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_87id0rf4pm5daha5tlg1671tdv