Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update

The global burden of viral infection, especially the current pandemics of SARS-CoV-2, HIV/AIDS, and hepatitis, is a very risky one. Additionally, HCV expresses the necessity for antiviral therapeutic elements. Venoms are known to contain an array of bioactive peptides that are commonly used in the t...

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Autores principales: El Hidan, Moulay Abdelmonaim, Laaradia, Mehdi Ait, El Hiba, Omar, Draoui, Ahmed, Aimrane, Abdelmohcine, Kahime, Kholoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437663/
https://www.ncbi.nlm.nih.gov/pubmed/34527748
http://dx.doi.org/10.1155/2021/9998420
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author El Hidan, Moulay Abdelmonaim
Laaradia, Mehdi Ait
El Hiba, Omar
Draoui, Ahmed
Aimrane, Abdelmohcine
Kahime, Kholoud
author_facet El Hidan, Moulay Abdelmonaim
Laaradia, Mehdi Ait
El Hiba, Omar
Draoui, Ahmed
Aimrane, Abdelmohcine
Kahime, Kholoud
author_sort El Hidan, Moulay Abdelmonaim
collection PubMed
description The global burden of viral infection, especially the current pandemics of SARS-CoV-2, HIV/AIDS, and hepatitis, is a very risky one. Additionally, HCV expresses the necessity for antiviral therapeutic elements. Venoms are known to contain an array of bioactive peptides that are commonly used in the treatment of various medical issues. Several peptides isolated from scorpion venom have recently been proven to possess an antiviral activity against several viral families. The aim of this review is to provide an up-to-date overview of scorpion antiviral peptides and to discuss their modes of action and potential biomedical application against different viruses.
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spelling pubmed-84376632021-09-14 Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update El Hidan, Moulay Abdelmonaim Laaradia, Mehdi Ait El Hiba, Omar Draoui, Ahmed Aimrane, Abdelmohcine Kahime, Kholoud Biomed Res Int Review Article The global burden of viral infection, especially the current pandemics of SARS-CoV-2, HIV/AIDS, and hepatitis, is a very risky one. Additionally, HCV expresses the necessity for antiviral therapeutic elements. Venoms are known to contain an array of bioactive peptides that are commonly used in the treatment of various medical issues. Several peptides isolated from scorpion venom have recently been proven to possess an antiviral activity against several viral families. The aim of this review is to provide an up-to-date overview of scorpion antiviral peptides and to discuss their modes of action and potential biomedical application against different viruses. Hindawi 2021-09-04 /pmc/articles/PMC8437663/ /pubmed/34527748 http://dx.doi.org/10.1155/2021/9998420 Text en Copyright © 2021 Moulay Abdelmonaim El Hidan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
El Hidan, Moulay Abdelmonaim
Laaradia, Mehdi Ait
El Hiba, Omar
Draoui, Ahmed
Aimrane, Abdelmohcine
Kahime, Kholoud
Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title_full Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title_fullStr Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title_full_unstemmed Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title_short Scorpion-Derived Antiviral Peptides with a Special Focus on Medically Important Viruses: An Update
title_sort scorpion-derived antiviral peptides with a special focus on medically important viruses: an update
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437663/
https://www.ncbi.nlm.nih.gov/pubmed/34527748
http://dx.doi.org/10.1155/2021/9998420
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