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Comparison of SARS-CoV-2 variant lethality in human angiotensin-converting enzyme 2 transgenic mice

This study compared the lethality of severe acute respiratory syndrome coronavirus 2 variants belonging to the S, V, L, G, GH, and GR clades using K18-human angiotensin-converting enzyme 2 heterozygous mice. To estimate the 50% lethal dose (LD(50)) of each variant, increasing viral loads (10(0)–10(4...

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Detalles Bibliográficos
Autores principales:	Lee, Tae-Young, Lee, Hansaem, Kim, Nayoung, Jeon, Pyeonghwa, Kim, Jun-Won, Lim, Hee-Young, Yang, Jeong-Sun, Kim, Kyung-Chang, Lee, Joo-Yeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Published by Elsevier B.V. 2021
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437746/ https://www.ncbi.nlm.nih.gov/pubmed/34530046 http://dx.doi.org/10.1016/j.virusres.2021.198563

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