Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati

Cryptic species in Aspergillus section Fumigati are increasingly reported to cause invasive aspergillosis in humans and animals. These infections are often refractory to treatment because of intrinsic antifungal resistance. We report two cases of invasive fungal rhinosinusitis in domestic cats cause...

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Autores principales: Kay, Alexandra, Boland, Lara, Kidd, Sarah E., Beatty, Julia A., Talbot, Jessica J., Barrs, Vanessa R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437771/
https://www.ncbi.nlm.nih.gov/pubmed/34540573
http://dx.doi.org/10.1016/j.mmcr.2021.08.005
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author Kay, Alexandra
Boland, Lara
Kidd, Sarah E.
Beatty, Julia A.
Talbot, Jessica J.
Barrs, Vanessa R.
author_facet Kay, Alexandra
Boland, Lara
Kidd, Sarah E.
Beatty, Julia A.
Talbot, Jessica J.
Barrs, Vanessa R.
author_sort Kay, Alexandra
collection PubMed
description Cryptic species in Aspergillus section Fumigati are increasingly reported to cause invasive aspergillosis in humans and animals. These infections are often refractory to treatment because of intrinsic antifungal resistance. We report two cases of invasive fungal rhinosinusitis in domestic cats caused by A. udagawae and A. felis. Clinical signs resolved after combined therapy including posaconazole, caspofungin and terbinafine. Both cases remained asymptomatic more than 2 years from initial presentation.
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spelling pubmed-84377712021-09-17 Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati Kay, Alexandra Boland, Lara Kidd, Sarah E. Beatty, Julia A. Talbot, Jessica J. Barrs, Vanessa R. Med Mycol Case Rep Case Report Cryptic species in Aspergillus section Fumigati are increasingly reported to cause invasive aspergillosis in humans and animals. These infections are often refractory to treatment because of intrinsic antifungal resistance. We report two cases of invasive fungal rhinosinusitis in domestic cats caused by A. udagawae and A. felis. Clinical signs resolved after combined therapy including posaconazole, caspofungin and terbinafine. Both cases remained asymptomatic more than 2 years from initial presentation. Elsevier 2021-09-02 /pmc/articles/PMC8437771/ /pubmed/34540573 http://dx.doi.org/10.1016/j.mmcr.2021.08.005 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kay, Alexandra
Boland, Lara
Kidd, Sarah E.
Beatty, Julia A.
Talbot, Jessica J.
Barrs, Vanessa R.
Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title_full Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title_fullStr Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title_full_unstemmed Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title_short Complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic Aspergillus species in section Fumigati
title_sort complete clinical response to combined antifungal therapy in two cats with invasive fungal rhinosinusitis caused by cryptic aspergillus species in section fumigati
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437771/
https://www.ncbi.nlm.nih.gov/pubmed/34540573
http://dx.doi.org/10.1016/j.mmcr.2021.08.005
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