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Landscape of functional interactions of human processive ribonucleases revealed by high-throughput siRNA screenings

Processive exoribonucleases are executors of RNA decay. In humans, their physical but not functional interactions were thoughtfully investigated. Here we have screened cells deficient in DIS3, XRN2, EXOSC10, DIS3L, and DIS3L2 with a custom siRNA library and determined their genetic interactions (GIs...

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Detalles Bibliográficos
Autores principales:	Hojka-Osinska, Anna, Chlebowski, Aleksander, Grochowska, Joanna, Owczarek, Ewelina P., Affek, Kamila, Kłosowska-Kosicka, Kamila, Szczesny, Roman J., Dziembowski, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437785/ https://www.ncbi.nlm.nih.gov/pubmed/34541468 http://dx.doi.org/10.1016/j.isci.2021.103036

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