Positron emission tomography imaging of serotonin degeneration and beta-amyloid deposition in late-life depression evaluated with multi-modal partial least squares

Depression in late-life is associated with increased risk of cognitive decline and development of all-cause dementia. The neurobiology of late-life depression (LLD) may involve both neurochemical and neurodegenerative mechanisms that are common to depression and dementia. Transgenic amyloid mouse mo...

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Detalles Bibliográficos
Autores principales: Smith, Gwenn S., Workman, Clifford I., Protas, Hillary, Su, Yi, Savonenko, Alena, Kuwabara, Hiroto, Gould, Neda F., Kraut, Michael, Joo, Jin Hui, Nandi, Ayon, Avramopoulos, Dimitri, Reiman, Eric M., Chen, Kewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437937/
https://www.ncbi.nlm.nih.gov/pubmed/34518514
http://dx.doi.org/10.1038/s41398-021-01539-9

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