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Optimization of psoriasis assessment system based on patch images
Psoriasis is a chronic inflammatory skin disease that occurs in various forms throughout the body and is associated with certain conditions such as heart disease, diabetes, and depression. The psoriasis area severity index (PASI) score, a tool used to evaluate the severity of psoriasis, is currently...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437948/ https://www.ncbi.nlm.nih.gov/pubmed/34518578 http://dx.doi.org/10.1038/s41598-021-97211-9 |
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author | Moon, Cho-I. Lee, Jiwon Yoo, HyunJong Baek, YooSang Lee, Onseok |
author_facet | Moon, Cho-I. Lee, Jiwon Yoo, HyunJong Baek, YooSang Lee, Onseok |
author_sort | Moon, Cho-I. |
collection | PubMed |
description | Psoriasis is a chronic inflammatory skin disease that occurs in various forms throughout the body and is associated with certain conditions such as heart disease, diabetes, and depression. The psoriasis area severity index (PASI) score, a tool used to evaluate the severity of psoriasis, is currently used in clinical trials and clinical research. The determination of severity is based on the subjective judgment of the clinician. Thus, the disease evaluation deviations are induced. Therefore, we propose optimal algorithms that can effectively segment the lesion area and classify the severity. In addition, a new dataset on psoriasis was built, including patch images of erythema and scaling. We performed psoriasis lesion segmentation and classified the disease severity. In addition, we evaluated the best-performing segmentation method and classifier and analyzed features that are highly related to the severity of psoriasis. In conclusion, we presented the optimal techniques for evaluating the severity of psoriasis. Our newly constructed dataset improved the generalization performance of psoriasis diagnosis and evaluation. It proposed an optimal system for specific evaluation indicators of the disease and a quantitative PASI scoring method. The proposed system can help to evaluate the severity of localized psoriasis more accurately. |
format | Online Article Text |
id | pubmed-8437948 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84379482021-09-15 Optimization of psoriasis assessment system based on patch images Moon, Cho-I. Lee, Jiwon Yoo, HyunJong Baek, YooSang Lee, Onseok Sci Rep Article Psoriasis is a chronic inflammatory skin disease that occurs in various forms throughout the body and is associated with certain conditions such as heart disease, diabetes, and depression. The psoriasis area severity index (PASI) score, a tool used to evaluate the severity of psoriasis, is currently used in clinical trials and clinical research. The determination of severity is based on the subjective judgment of the clinician. Thus, the disease evaluation deviations are induced. Therefore, we propose optimal algorithms that can effectively segment the lesion area and classify the severity. In addition, a new dataset on psoriasis was built, including patch images of erythema and scaling. We performed psoriasis lesion segmentation and classified the disease severity. In addition, we evaluated the best-performing segmentation method and classifier and analyzed features that are highly related to the severity of psoriasis. In conclusion, we presented the optimal techniques for evaluating the severity of psoriasis. Our newly constructed dataset improved the generalization performance of psoriasis diagnosis and evaluation. It proposed an optimal system for specific evaluation indicators of the disease and a quantitative PASI scoring method. The proposed system can help to evaluate the severity of localized psoriasis more accurately. Nature Publishing Group UK 2021-09-13 /pmc/articles/PMC8437948/ /pubmed/34518578 http://dx.doi.org/10.1038/s41598-021-97211-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Moon, Cho-I. Lee, Jiwon Yoo, HyunJong Baek, YooSang Lee, Onseok Optimization of psoriasis assessment system based on patch images |
title | Optimization of psoriasis assessment system based on patch images |
title_full | Optimization of psoriasis assessment system based on patch images |
title_fullStr | Optimization of psoriasis assessment system based on patch images |
title_full_unstemmed | Optimization of psoriasis assessment system based on patch images |
title_short | Optimization of psoriasis assessment system based on patch images |
title_sort | optimization of psoriasis assessment system based on patch images |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437948/ https://www.ncbi.nlm.nih.gov/pubmed/34518578 http://dx.doi.org/10.1038/s41598-021-97211-9 |
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