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OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection

Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS. Optineurin (OPTN) is...

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Detalles Bibliográficos
Autores principales:	Ames, Joshua, Yadavalli, Tejabhiram, Suryawanshi, Rahul, Hopkins, James, Agelidis, Alexander, Patil, Chandrashekhar, Fredericks, Brian, Tseng, Henry, Valyi-Nagy, Tibor, Shukla, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437952/ https://www.ncbi.nlm.nih.gov/pubmed/34518549 http://dx.doi.org/10.1038/s41467-021-25642-z

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