Cargando…
Sirtuin 3 regulates mitochondrial protein acetylation and metabolism in tubular epithelial cells during renal fibrosis
Proximal tubular epithelial cells (TECs) demand high energy and rely on mitochondrial oxidative phosphorylation as the main energy source. However, this is disturbed in renal fibrosis. Acetylation is an important post-translational modification for mitochondrial metabolism. The mitochondrial protein...
Autores principales: | Zhang, Yu, Wen, Ping, Luo, Jing, Ding, Hao, Cao, Hongdi, He, Weichun, Zen, Ke, Zhou, Yang, Yang, Junwei, Jiang, Lei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437958/ https://www.ncbi.nlm.nih.gov/pubmed/34518519 http://dx.doi.org/10.1038/s41419-021-04134-4 |
Ejemplares similares
-
A microRNA-30e/mitochondrial uncoupling protein 2 axis mediates TGF-β1-induced tubular epithelial cell extracellular matrix production and kidney fibrosis
por: Jiang, Lei, et al.
Publicado: (2013) -
Uric Acid Induces Renal Inflammation via Activating Tubular NF-κB Signaling Pathway
por: Zhou, Yang, et al.
Publicado: (2012) -
Involvement of Endoplasmic Reticulum Stress in Albuminuria Induced Inflammasome Activation in Renal Proximal Tubular Cells
por: Fang, Li, et al.
Publicado: (2013) -
Sirtuin 5 depletion impairs mitochondrial function in human proximal tubular epithelial cells
por: Haschler, Timo N., et al.
Publicado: (2021) -
Lysine Acetylation in the Proteome of Renal Tubular Epithelial Cells in Diabetic Nephropathy
por: Wan, Jiayi, et al.
Publicado: (2021)