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B cell depletion with anti-CD20 mAb exacerbates anti-donor CD4(+) T cell responses in highly sensitized transplant recipients

Pretransplant desensitization with rituximab has been applied to preformed donor-specific anti-human leukocyte antigen antibody (DSA)-positive recipients for elimination of preformed DSA. We investigated the impact of pretransplant desensitization with rituximab on anti-donor T cell responses in DSA...

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Detalles Bibliográficos
Autores principales: Tanaka, Asuka, Ide, Kentaro, Tanaka, Yuka, Ohira, Masahiro, Tahara, Hiroyuki, Ohdan, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437972/
https://www.ncbi.nlm.nih.gov/pubmed/34518640
http://dx.doi.org/10.1038/s41598-021-97748-9