Cargando…

Human age-declined saliva metabolic markers determined by LC–MS

Metabolites in human biofluids reflect individual physiological states influenced by various factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non-targeted, non-invasive metabolomics using saliva of 27 healthy volunteers in Okinawa, comprising 13 young (30 ± 3 year) and 14...

Descripción completa

Detalles Bibliográficos
Autores principales:	Teruya, Takayuki, Goga, Haruhisa, Yanagida, Mitsuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437986/ https://www.ncbi.nlm.nih.gov/pubmed/34518599 http://dx.doi.org/10.1038/s41598-021-97623-7

Ejemplares similares

Aging markers in human urine: A comprehensive, non‐targeted LC‐MS study
por: Teruya, Takayuki, et al.
Publicado: (2020)

Development and Validation of LC-MS/MS Method for Determination of Cytisine in Human Serum and Saliva
por: Wróblewski, Karol, et al.
Publicado: (2023)

Development and validation of an LC-MS/MS method for determination of 8-iso-prostaglandin f2 Alpha in human saliva
por: Tomova, Zlatina, et al.
Publicado: (2022)

Frailty markers comprise blood metabolites involved in antioxidation, cognition, and mobility
por: Kameda, Masahiro, et al.
Publicado: (2020)

Reduced uremic metabolites are prominent feature of sarcopenia, distinct from antioxidative markers for frailty
por: Kameda, Masahiro, et al.
Publicado: (2021)

Metabolomics of human fasting: new insights about old questions
por: Kondoh, Hiroshi, et al.
Publicado: (2020)

Diverse metabolic reactions activated during 58-hr fasting are revealed by non-targeted metabolomic analysis of human blood
por: Teruya, Takayuki, et al.
Publicado: (2019)

Markers for obese and non-obese Type 2 diabetes identified using whole blood metabolomics
por: Teruya, Takayuki, et al.
Publicado: (2023)

Development and Validation of an LC-MS/MS Method and Comparison with a GC-MS Method to Measure Phenytoin in Human Brain Dialysate, Blood, and Saliva
por: Hösli, Raphael, et al.
Publicado: (2018)

Comparison of EI-GC-MS/MS, APCI-LC-MS/MS, and ESI-LC-MS/MS for the Simultaneous Analysis of Nine Nitrosamines Eluted from Synthetic Resins into Artificial Saliva and Health Risk Assessment
por: Kim, Hyungsoo, et al.
Publicado: (2021)

Liquid Chromatography Mass Spectrometry (LC-MS) analysis in determining the saliva protein of orthodontic patients during retention phase
por: Awang-Kechik, Noor-Hidayah, et al.
Publicado: (2019)

Analytical Challenges: Determination of Tetrodotoxin in Human Urine and Plasma by LC-MS/MS
por: Leung, Kelvin Sze-Yin, et al.
Publicado: (2011)

Development and Validation of a Simple LC-MS Method for the Quantification of Oxytocin in Dog Saliva
por: Wang, Lei, et al.
Publicado: (2019)

Absorption and Metabolism Characteristics of Triptolide as Determined by a Sensitive and Reliable LC-MS/MS Method
por: Gong, Xiaomei, et al.
Publicado: (2015)

LC-MS/MS and LC-UV Determination of Moniliformin by Adding Lanthanide Ions to the Mobile Phase
por: Bertuzzi, Terenzio, et al.
Publicado: (2019)

Determination of Salicylic Acid in Feed Using LC-MS/MS
por: Protasiuk, Edyta, et al.
Publicado: (2018)

Targeted Determination of Tissue Energy Status by LC-MS/MS
por: Fu, Xiaorong, et al.
Publicado: (2019)

Reply to Pan et al.: Whole blood metabolome analysis combined with comprehensive frailty assessment
por: Kameda, Masahiro, et al.
Publicado: (2021)

Development of an LC−MS/MS method for determination of 2-oxo-clopidogrel in human plasma
por: Li, Yu-Han, et al.
Publicado: (2015)

Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS
por: Patel, Nirav P., et al.
Publicado: (2018)

Peptide Markers for Rapid Detection of KPC Carbapenemase by LC-MS/MS
por: Wang, Honghui, et al.
Publicado: (2017)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

Determination of the Metabolites and Metabolic Pathways for Three β-Receptor Agonists in Rats Based on LC-MS/MS
por: Liang, Ying, et al.
Publicado: (2022)

Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma
por: Attwa, Mohamed W., et al.
Publicado: (2018)

Validation by collaborative trial of a method for the determination by GC–MS and LC–MS/MS of boar taint marker compounds in pork tissue
por: Buttinger, Gerhard, et al.
Publicado: (2020)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

Fast and sensitive LC–MS/MS method for the simultaneous determination of lisinopril and hydrochlorothiazide in human plasma
por: Shah, Jaivik V., et al.
Publicado: (2017)

LC–MS/MS Method for the Simultaneous Determination of Free Urinary Steroids
por: Allende, Fidel, et al.
Publicado: (2014)

Determination and pharmacokinetics study of oxyclozanide suspension in cattle by LC-MS/MS
por: Zhang, Jili, et al.
Publicado: (2019)

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats
por: Chen, Juan, et al.
Publicado: (2022)

Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS
por: Wei, Qi, et al.
Publicado: (2022)

Determination of 355 Pesticides in Lemon and Lemon Juice by LC-MS/MS and GC-MS/MS
por: Aslantas, Sule, et al.
Publicado: (2023)

S-Adenosylmethionine Synthetase Is Required for Cell Growth, Maintenance of G0 Phase, and Termination of Quiescence in Fission Yeast
por: Hayashi, Takeshi, et al.
Publicado: (2018)

Development and validation of an LC-MS/MS method for determination of compound K in human plasma and clinical application
por: Kim, Jung Soo, et al.
Publicado: (2013)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Development and Validation of an LC-MS/MS Method for the Quantitative Determination of Contezolid in Human Plasma and Cerebrospinal Fluid
por: Zhang, Guanxuanzi, et al.
Publicado: (2022)

Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC–MS/MS and evaluation of their stability in mice tissues
por: Krijt, Jakub, et al.
Publicado: (2009)

Development of LC-MS/MS Confirmatory Method for the Determination of Testosterone in Bovine Serum
por: Woźniak, Barbara, et al.
Publicado: (2017)

Simultaneous Determination of Acrylamide and Hydroxymethylfurfural in Extruded Products by LC-MS/MS Method
por: Jozinović, Antun, et al.
Publicado: (2019)

Multiple Mycotoxins Determination in Food by LC-MS/MS: An International Collaborative Study
por: Bessaire, Thomas, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_utuvmftk58tdk3svs67rrkf7st