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Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence

Emerging evidence suggests that contact tracing has had limited success in the UK in reducing the R number across the COVID-19 pandemic. We investigate potential pitfalls and areas for improvement by extending an existing branching process contact tracing model, adding diagnostic testing and refinin...

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Autores principales: Davis, Emma L., Lucas, Tim C. D., Borlase, Anna, Pollington, Timothy M., Abbott, Sam, Ayabina, Diepreye, Crellen, Thomas, Hellewell, Joel, Pi, Li, Medley, Graham F., Hollingsworth, T. Déirdre, Klepac, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438018/
https://www.ncbi.nlm.nih.gov/pubmed/34518525
http://dx.doi.org/10.1038/s41467-021-25531-5
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author Davis, Emma L.
Lucas, Tim C. D.
Borlase, Anna
Pollington, Timothy M.
Abbott, Sam
Ayabina, Diepreye
Crellen, Thomas
Hellewell, Joel
Pi, Li
Medley, Graham F.
Hollingsworth, T. Déirdre
Klepac, Petra
author_facet Davis, Emma L.
Lucas, Tim C. D.
Borlase, Anna
Pollington, Timothy M.
Abbott, Sam
Ayabina, Diepreye
Crellen, Thomas
Hellewell, Joel
Pi, Li
Medley, Graham F.
Hollingsworth, T. Déirdre
Klepac, Petra
author_sort Davis, Emma L.
collection PubMed
description Emerging evidence suggests that contact tracing has had limited success in the UK in reducing the R number across the COVID-19 pandemic. We investigate potential pitfalls and areas for improvement by extending an existing branching process contact tracing model, adding diagnostic testing and refining parameter estimates. Our results demonstrate that reporting and adherence are the most important predictors of programme impact but tracing coverage and speed plus diagnostic sensitivity also play an important role. We conclude that well-implemented contact tracing could bring small but potentially important benefits to controlling and preventing outbreaks, providing up to a 15% reduction in R. We reaffirm that contact tracing is not currently appropriate as the sole control measure.
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spelling pubmed-84380182021-09-24 Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence Davis, Emma L. Lucas, Tim C. D. Borlase, Anna Pollington, Timothy M. Abbott, Sam Ayabina, Diepreye Crellen, Thomas Hellewell, Joel Pi, Li Medley, Graham F. Hollingsworth, T. Déirdre Klepac, Petra Nat Commun Article Emerging evidence suggests that contact tracing has had limited success in the UK in reducing the R number across the COVID-19 pandemic. We investigate potential pitfalls and areas for improvement by extending an existing branching process contact tracing model, adding diagnostic testing and refining parameter estimates. Our results demonstrate that reporting and adherence are the most important predictors of programme impact but tracing coverage and speed plus diagnostic sensitivity also play an important role. We conclude that well-implemented contact tracing could bring small but potentially important benefits to controlling and preventing outbreaks, providing up to a 15% reduction in R. We reaffirm that contact tracing is not currently appropriate as the sole control measure. Nature Publishing Group UK 2021-09-13 /pmc/articles/PMC8438018/ /pubmed/34518525 http://dx.doi.org/10.1038/s41467-021-25531-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Davis, Emma L.
Lucas, Tim C. D.
Borlase, Anna
Pollington, Timothy M.
Abbott, Sam
Ayabina, Diepreye
Crellen, Thomas
Hellewell, Joel
Pi, Li
Medley, Graham F.
Hollingsworth, T. Déirdre
Klepac, Petra
Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title_full Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title_fullStr Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title_full_unstemmed Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title_short Contact tracing is an imperfect tool for controlling COVID-19 transmission and relies on population adherence
title_sort contact tracing is an imperfect tool for controlling covid-19 transmission and relies on population adherence
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438018/
https://www.ncbi.nlm.nih.gov/pubmed/34518525
http://dx.doi.org/10.1038/s41467-021-25531-5
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