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Deimmunization of flagellin for repeated administration as a vaccine adjuvant

Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should lead to antibody responses precluding repeated administration, the development of flagellin...

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Detalles Bibliográficos
Autores principales: Khim, Koemchhoy, Bang, Yong Jun, Puth, Sao, Choi, Yoonjoo, Lee, Youn Suhk, Jeong, Kwangjoon, Lee, Shee Eun, Rhee, Joon Haeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438039/
https://www.ncbi.nlm.nih.gov/pubmed/34518537
http://dx.doi.org/10.1038/s41541-021-00379-4