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Deimmunization of flagellin for repeated administration as a vaccine adjuvant
Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should lead to antibody responses precluding repeated administration, the development of flagellin...
Autores principales: | Khim, Koemchhoy, Bang, Yong Jun, Puth, Sao, Choi, Yoonjoo, Lee, Youn Suhk, Jeong, Kwangjoon, Lee, Shee Eun, Rhee, Joon Haeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8438039/ https://www.ncbi.nlm.nih.gov/pubmed/34518537 http://dx.doi.org/10.1038/s41541-021-00379-4 |
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